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Table 1 Main effects observed between groups after 2 months of soybean beverage intake in cardiovascular disease risk parameters

From: Vitamin D receptor BsmI polymorphism modulates soy intake and 25-hydroxyvitamin D supplementation benefits in cardiovascular disease risk factors profile

 

Basal

2 months

p

A. Soy beverage 1 (250 mL/day)

 Lipid profile (mg/dL)

  Total cholesterol

183.7 ± 29.1

183.4 ± 27.4

0.879

  LDL

109.0 ± 26.1

107.4 ± 26.3

0.367

  HDL

68.3 ± 11.4

70.3 ± 10.4

0.124

  Triglycerides

96.2 ± 43.0

95.9 ± 37.1

0.954

 Blood pressure (mmHg)

  Systolic

122 ± 13

118 ± 9

0.042

  Diastolic

82 ± 11

76 ± 7

0.006

 Inflammation biomarkers (pg/mL)

  TNFα

4.5 ± 1.3

4.3 ± 1.4

0.447

  MCP-1

321 ± 96

313 ± 98

0.548

 Vitamin D (ng/mL)

  25 D3

18.0 ± 5.6

25.0 ± 5.4

<0.001

  1,25 D3

0.32 ± 0.10

0.32 ± 0.11

0.468

  24R,25 D3

2.3 ± 1.5

2.6 ± 1.8

0.823

B. Soy beverage 2 (500 mL/day)

 Lipid profile (mg/dL)

  Total cholesterol

180.3 ± 29.2

179.6 ± 30.0

0.820

  LDL

107.1 ± 25.2

105.2 ± 24.6

0.482

  HDL

68.5 ± 12.4

71.0 ± 12.6

0.111

  Triglycerides

79.9 ± 25.7

74.7 ± 17.5

0.323

 Blood pressure (mmHg)

  Systolic

120 ± 9

116 ± 10

0.075

  Diastolic

75 ± 7

74 ± 8

0.310

 Inflammation biomarkers (pg/mL)

  TNFα

4.8 ± 1.6

4.6 ± 1.4

0.306

  MCP-1

334 ± 82

339 ± 88

0.638

 Vitamin D (ng/mL)

  25 D3

20.5 ± 6.3

26.0 ± 5.2

<0.001

  1,25 D3

0.29 ± 0.12

0.34 ± 0.11

0.498

  24R,25 D3

2.8 ± 1.4

2.6 ± 1.3

0.050

C. Control

 Lipid profile (mg/dL)

  Total cholesterol

176.4 ± 29.6

176.8 ± 32.3

0.883

  LDL

104.6 ± 26.6

101.0 ± 26.9

0.154

  HDL

64.6 ± 13.8

66.9 ± 13.0

0.077

  Triglycerides

93.3 ± 37.8

98.9 ± 43.5

0.604

 Blood pressure (mmHg)

  Systolic

124 ± 13

116 ± 12

0.003

  Diastolic

75 ± 10

73 ± 8

0.624

 Inflammation biomarkers (pg/mL)

  TNFα

4.0 ± 1.2

4.2 ± 1.3

0.042

  MCP-1

308 ± 103

320 ± 107

0.266

 Vitamin D (ng/mL)

  25 D3

20.3 ± 6.0

21.2 ± 5.5

0.251

  1,25 D3

0.42 ± 0.08

0.35 ± 0.08

0.497

  24R,25 D3

3.1 ± 0.7

2.8 ± 1.2

0.096

  1. Paired t Student test was performed within each one of the groups for the different parameters analyzed. Statistically differences were observed between basal and after 2 months of treatments in the levels of 25(OH)D3 in the soy beverage group 1 and 2