Skip to main content

Table 4 mRNA expression levels of genes involved in lipid metabolism in PBMCs samples of male and female offspring of control and calorie-restricted dams during lactation (CR) at the age of 6 months

From: Identification of early transcriptome-based biomarkers related to lipid metabolism in peripheral blood mononuclear cells of rats nutritionally programmed for improved metabolic health

 

Males

Females

ANOVA

Control

CR

Control

CR

Apob48r

100 ± 12

101 ± 12

100 ± 23

110 ± 20

 

Cpt1a

100 ± 5

102 ± 8

114 ± 12

84.4 ± 3.6*

 

Fasn

100 ± 8

109 ± 8

126 ± 4

99.7 ± 4.8*

RxS

Lipe

100 ± 13

107 ± 12

91.9 ± 5.2

92.4 ± 12.4

 

Lrp1

100 ± 25

139 ± 39

73.8 ± 13.5

110 ± 13.2

 

Pcyt2

100 ± 19

121 ± 28

84.1 ± 8.8

109 ± 22

 

Rxrb

100 ± 6

115 ± 6

125 ± 10

103 ± 4

RxS

Sorl1

100 ± 21

96.5 ± 16.1

75.7 ± 2.5

103 ± 18

 

Star

100 ± 15

137 ± 22

120 ± 10

167 ± 33

R (p = 0.077)

  1. mRNA levels were measured under ad libitum feeding conditions at the age of 6 months by RT-qPCR and expressed as a percentage of the mean value of males control. Data are mean ± SEM (n = 6–8 animals/group). Statistics: R, effect of maternal calorie restriction during lactation; RxS, an interaction between the effect of maternal calorie restriction during lactation and the effect of sex (p < 0.05; two-way ANOVA). *, CR vs Controls (p < 0.05; Student’s t test)
Back to article page

Genes & Nutrition

ISSN: 1865-3499

Contact us