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Table 2 Pharmacological response of the dopamine system

From: Prenatal iron deficiency and monoamine oxidase A (MAOA) polymorphisms: combined risk for later cognitive performance in rhesus monkeys

 

Hi-MAOA

Low-MAOA

IS

ID

IS

ID

Vehicle session: reinforcements*

9.1 ± 0.1a

9.3 ± 0.2

9.3 ± 0.2

8.0 ± 0.7**

Vehicle session: responses

184 ± 37

175 ± 20

181 ± 38

87 ± 8

Haloperidol session: change in number of responses

−163 ± 48

−151 ± 31

−141 ± 48

−1 ± 29

Haloperidol + apomorphine: change in number of responses***

−149 ± 51

−79 ± 21

−124 ± 32

−67 ± 26

  1. See text for interpretation
  2. * Significant MAOA by ID interaction by ANOVA, p < 0.02
  3. ** Significant IS/ID post hoc comparison within low-MAOA group, p < 0.01
  4. *** Significant ID effect by ANOVA, p < .05
  5. aMean ± sem