Table 4 Multivariable-adjusted means and differences (95 % CI) for the association between each of the SNPs and cognitive assessment (Clock Drawing Test) according to intervention status

Means (95 % CI)

5.18 (4.98 to 5.38)

5.33 (5.17 to 5.49)

Adj. diff.

0 (Ref.)

0.15 (−0.11 to 0.41)

p value

0.265

By intervention

Control (n = 45)

MedDiet^c (n = 153)

Control (n = 83)

MedDiet^c (n = 226)

Means (95 % CI)

4.83 (4.39 to 5.21)

5.24 (5.01 to 5.48)

4.90 (4.60 to 5.21)

5.50 (5.32 to 5.69)

B, Adj. diff. (95 % CI)^a

0 (Ref.)

0.40 (−0.11 to 0.92)

0 (Ref.)

0.60 (0.24 to 0.96)

p value (MedDiet vs. control)

0.126

0.001^d

p for interaction^b

0.366

Means (95 % CI)

5.28 (5.13 to 5.42)

5.26 (5.01 to 5.50)

Adj. differences

0 (Ref.)

−0.02 (−0.30 to 0.27)

p value

0.900

By intervention

Control (n = 97)

MedDiet^c (n = 278)

Control (n = 32)

MedDiet^c (n = 101)

Means (95 % CI)

4.96 (4.68 to 5.25)

5.43 (5.26 to 5.59)

4.92 (4.40 to 5.45)

5.24 (4.95 to 5.53)

B, Adj. diff. (95 % CI)^a

0 (Ref.)

0.46 (0.13 to 0.79)

0 (Ref.)

0.31 (−0.30 to 0.93)

p value (MedDiet vs. control)

0.006^d

0.762

p for interaction^b

0.841

Means (95 % CI)

5.35 (5.17 to 5.52)

5.21 (5.03 to 5.39)

Adj. differences

0 (Ref.)

−0.14 (−0.39 to 0.11)

p value

0.275

By intervention

Control (n = 60)

MedDiet^c (n = 196)

Control (n = 69)

MedDiet^c (n = 179)

Means (95 % CI)

5.19 (4.84 to 5.54)

5.41 (5.22 to 5.60)

4.78 (4.43 to 5.13)

5.36 (5.15 to 5.58)

B, Adj. diff. (95 % CI)^a

0 (Ref.)

0.27 (−0.13 to 0.68)

0 (Ref.)

0.59 (0.18 to 1.00)

p value (MedDiet vs. control)

0.186

0.005^d

p for interaction^b

0.133