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Table 3 Gene–diet interaction effects on the plasma TG response to fish oil

From: An interaction effect between glucokinase gene variation and carbohydrate intakes modulates the plasma triglyceride response to a fish oil supplementation

tSNPs

Genotype

β (interaction term)

P genotypea

P CHOa

P interaction effecta

rs2268573

C/C

0

0.94

0.05

0.96

A/C

0.0740 ± 0.5332

   

A/A

−0.1084 ± 0.6796

   

rs2908297

G/G

0

0.54

0.27

0.40

A/A+A/G

0.4819 ± 0.5730

   

rs2971676

C/C

0

0.73

0.23

0.70

T/T+C/T

0.2427 ± 0.6239

   

rs758989

A/A

0

0.62

0.04

0.67

A/G

0.4084 ± 0.5660

   

G/G

−0.0393 ± 0.5978

   

rs12673242

T/T

0

0.14

0.68

0.09

C/C+C/T

1.0556 ± 0.6198

   

rs2908290

C/C

0

0.65

0.07

0.65

C/T

0.3690 ± 0.4906

   

T/T

−0.2902 ± 0.8764

   

rs2284777

A/A

0

0.48

0.04

0.50

G/G+A/G

−0.3345 ± 0.4975

   

rs2300584

T/T

0

0.38

0.04

0.36

C/C+C/T

−0.4474 ± 0.4880

   

rs1990458

G/G

0

0.09

0.07

0.07

A/G

1.1604 ± 0.5029

   

A/A

0.4946 ± 0.7105

   

rs741038

T/T

0

0.01

0.0004

0.008

C/T

0.3766 ± 0.4779

   

C/C

−2.4272 ± 0.9010

   

rs1799884

G/G

0

0.73

0.05

0.78

A/A+A/G

−0.1385 ± 0.4847

   

rs2908277

C/C

0

0.97

0.08

0.83

T/T+C/T

−0.1151 ± 0.5440

   

rs3757838

T/T

0

0.18

0.03

0.19

A/A+A/T

−1.0834 ± 0.8202

   
  1. Mean ± SD
  2. a p values of the GLM models are adjusted for age, sex and BMI