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Table 3 Association among age groups, GRS groups, and indicators of body fatness (n = 181)

From: Strong influence of dietary intake and physical activity on body fatness in elderly Japanese men: age-associated loss of polygenic resistance against obesity

Age group

Middle-aged (30–64 years)

Elderly (65–79 years)

Age

GRS

Interaction

GRS

Low

Middle

High

Low

Middle

High

p

p

p

n

30

25

29

37

31

29

   

Age (year)

52.5 ± 11.8

54.0 ± 11.9

53.7 ± 10.8

69.0 ± 3.5

70.0 ± 3.9

71.3 ± 3.9

<0.001

0.473

0.881

Body weight (kg)

66.3 ± 5.9

72.0 ± 8.3

72.7 ± 12.2*

67.4 ± 9.7

65.4 ± 8.2

67.1 ± 9.1

0.282

0.152

0.047

BMI (kg/m2)

22.7 ± 1.8

24.3 ± 2.2*

24.9 ± 3.5*

23.5 ± 2.6

23.4 ± 2.4

23.4 ± 1.9†

0.160

0.067

0.019

Body fat (%)

18.5 ± 4.2

20.4 ± 4.8

21.1 ± 5.1

21.5 ± 4.9

20.7 ± 4.7

20.6 ± 3.1

0.715

0.722

0.059

Waist circumference (cm)

80.2 ± 6.8

85.9 ± 7.0*

86.3 ± 9.1*

85.6 ± 7.2

84.3 ± 6.5

85.3 ± 6.3

0.310

0.125

0.010

Total abdominal fat (cm2)

183.0 ± 79.9

231.9 ± 85.7

257.4 ± 98.5*

239.6 ± 80.3†

226.8 ± 70.5

221.2 ± 68.8

0.782

0.234

0.005

Visceral fat (cm2)

85.7 ± 45.4

109.0 ± 47.6

124.4 ± 48.6*

120.7 ± 48.9

113.6 ± 42.0

115.7 ± 52.8

0.504

0.299

0.023

Subcutaneous fat (cm2)

97.4 ± 40.3

122.9 ± 53.6

133.0 ± 63.0*

118.9 ± 45.4†

113.2 ± 41.3

105.5 ± 27.8

0.847

0.332

0.012

  1. Data are mean ± SD values. Data were analyzed by two-way ANCOVA adjusted for age, current/former smoking status, and type 2 diabetes
  2. BMI body mass index, GRS genetic risk score
  3. Boldface indicates significance (p < 0.05)
  4. * p < 0.05 versus the low GRS group within the same age group
  5. † p < 0.05 versus middle-aged group within the same GRS group