Table 2 B vitamin status and tHcy according to genotype
N (%) | EGRACa,b | EASTACa,c | PFd (nmol/L) | B d12 (pmol/L) | tHcye (µmol/L) | |
|---|---|---|---|---|---|---|
All | 771 (100) | 1.38 (1.36, 1.39) | 1.66 (1.64, 1.68) | 11.5 (11.0, 11.9) | 346 (337, 355) | 9.55 (9.36, 9.75) |
MTHFR 677 | ||||||
CC | 276 (35.9) | 1.39 (1.36, 1.42) | 1.66 (1.63, 1.69) | 12.4 (11.6, 13.2) | 356 (342, 371) | 9.02 (8.74, 9.30) |
CT | 356 (46.3) | 1.38 (1.36, 1.41) | 1.66 (1.64, 1.69) | 11.3 (10.7, 12.0)*,† | 340 (328, 353) | 9.34 (9.10, 9.60)††† |
TT | 137 (17.8) | 1.35 (1.31, 1.39) | 1.66 (1.63, 1.70) | 10.1 (9.2, 11.1)*** | 340 (317, 363) | 11.35 (10.72, 12.02)*** |
MTRR 66 | ||||||
AA | 194 (25.9) | 1.39 (1.35, 1.43) | 1.68 (1.65, 1.70) | 11.0 (10.1, 11.9) | 356 (339, 374) | 9.26 (8.92, 9.62) |
AG | 375 (50.0) | 1.38 (1.35, 1.40) | 1.66 (1.64, 1.69) | 11.9 (11.2, 12.5) | 334 (321, 348)***,† | 9.55 (9.27, 9.84) |
GG | 181 (24.1) | 1.37 (1.34, 1.41) | 1.64 (1.61, 1.67) | 10.9 (10.1, 11.8) | 357 (341, 375) | 9.81 (9.39, 10.25) |
MTRR 524 | ||||||
CC | 302 (40.2) | 1.36 (1.34, 1.39) | 1.66 (1.64, 1.69) | 11.5 (10.8, 12.2) | 341 (327, 356) | 9.58 (9.30, 9.86) |
CT | 348 (46.3) | 1.39 (1.36, 1.42) | 1.66 (1.63, 1.68) | 11.3 (10.7, 12.0) | 346 (333, 359) | 9.60 (9.30, 9.90) |
TT | 101 (13.5) | 1.40 (1.35, 1.44) | 1.67 (1.62, 1.71) | 11.4 (10.3, 12.7) | 355 (331, 382) | 9.23 (8.64, 9.86) |