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Table 3 Association analysis of ADIPOQ genetic variants with adiponectin levels and eating behavior factors in the Sorbs

From: Role of genetic variants in ADIPOQ in human eating behavior

SNP 

Genotype

Gender

BMI

Adiponectin

Restraint

Disinhibition

Hunger

N

M/F

kg/m2

µg/ml

N = 548

N = 548

N = 547

rs864265

T/T N = 12

6/6

27.2 ± 4.2

16.44 ± 4.74

7.38 ± 4.08

2.63 ± 2.00

2.94 ± 1.48

T/G N = 178

70/108

26.8 ± 4.7

16.75 ± 5.17

8.09 ± 4.48

4.01 ± 2.70

3.58 ± 2.77

G/G N = 642

256/386

26.4 ± 4.7

16.56 ± 5.13

7.84 ± 5.03

4.45 ± 3.05

4.03 ± 2.82

P value

  

 n.s.

 n.s.

 n.s.

0.015 a

 n.s.

rs182052

A/A N = 154

62/92

26.9 ± 4.7

16.18 ± 4.99

7.75 ± 4.75

3.88 ± 2.81

3.59 ± 2.50

A/G N = 396

160/236

26.3 ± 4.7

16.88 ± 5.12

7.67 ± 4.83

4.47 ± 3.18

4.12 ± 3.00

G/G N = 284

113/171

26.5 ± 4.6

16.43 ± 5.22

8.22 ± 5.04

4.30 ± 2.77

3.76 ± 2.63

P value

  

 n.s.

 n.s.

 n.s.

 n.s.

 n.s.

rs16861205

A/A N = 3

1/2

28.2 ± 11.8

17.62 ± 3.40

10.00 ± 0.00

5.00 ± 0.00

0.00 ± 0.00

A/G N = 135

50/85

26.9 ± 5.3

16.00 ± 5.02

7.75 ± 4.83

4.55 ± 3.25

3.90 ± 3.22

G/G N = 697

283/414

26.4 ± 4.5

16.70 ± 5.15

7.90 ± 4.92

4.27 ± 2.93

3.92 ± 2.71

P value

  

 n.s.

 n.s.

 n.s.

 n.s.

 n.s.

rs17366568

A/A N = 12

3/9

22.5 ± 3.4

17.52 ± 4.52

6.61 ± 4.26

3.67 ± 3.71

3.94 ± 2.46

A/G N = 175

73/102

26.5 ± 4.6

15.81 ± 5.28

7.61 ± 4.83

4.32 ± 3.22

3.61 ± 2.90

G/G N = 649

259/390

26.6 ± 4.7

16.78 ± 5.08

7.98 ± 4.93

4.32 ± 2.89

3.98 ± 2.77

P value

  

 n.s.

0.027 a

 n.s.

 n.s.

 n.s.

rs2241767

G/G N = 2

0/2

27.2 ± 2.6

18.71 ± 5.08

12.00 ± 0.00

2.00 ± 0.00

1.00 ± 0.00

 

G/A N = 86

37/49

26.0 ± 4.3

16.84 ± 5.89

8.37 ± 4.52

4.69 ± 3.20

3.76 ± 2.59

 

A/A N = 747

298/449

26.6 ± 4.8

16.57 ± 5.03

7.81 ± 4.94

4.26 ± 2.94

3.91 ± 2.80

P value

  

 n.s.

 n.s.

 n.s.

 n.s.

 n.s.

rs3821799

T/T N = 138

54/84

26.2 ± 5.1

17.23 ± 5.53

6.99 ± 4.75

4.92 ± 2.95

4.31 ± 3.04

 

T/C N = 408

172/236

26.4 ± 4.4

16.49 ± 4.88

8.17 ± 5.09

4.14 ± 2.88

3.79 ± 2.69

 

C/C N = 289

110/179

26.9 ± 4.9

16.41 ± 5.27

7.87 ± 4.64

4.27 ± 3.09

3.90 ± 2.78

P value

  

 n.s.

 n.s.

 n.s.

 n.s.

 n.s.

rs3774261

A/A N = 94

36/58

26.0 ± 5.0

17.85 ± 5.20

7.46 ± 5.04

4.89 ± 2.92

4.17 ± 2.92

 

A/G N = 396

164/232

26.4 ± 4.4

16.61 ± 5.00

8.07 ± 5.16

4.34 ± 2.87

3.92 ± 2.81

 

G/G N = 347

136/211

26.8 ± 5.0

16.22 ± 5.21

7.80 ± 4.56

4.10 ± 3.09

3.81 ± 2.74

P value

  

 n.s.

0.006 a

 n.s.

0.019 a

 n.s.

rs822396

G/G N = 56

21/35

26.40 ± 4.67

17.57 ± 4.95

7.89 ± 4.4

3.49 ± 2.6

3.61 ± 2.6

 

A/G N = 288

117/171

26.95 ± 4.77

16.71 ± 4.81

8.06 ± 5.0

4.19 ± 2.9

3.86 ± 2.8

 

A/A N = 553

218/335

26.21 ± 4.58

16.48 ± 5.27

7.84 ± 4.9

4.52 ± 3.1

3.61 ± 2.6

P value

  

 n.s.

 n.s.

 n.s.

0.036 a

 n.s.

rs1501229

T/T N = 70

30/40

25.60 ± 4.63

17.70 ± 5.12

7.24 ± 5.35

4.81 ± 2.70

3.78 ± 2.68

 

G/T N = 387

154/233

26.55 ± 4.51

16.80 ± 4.90

8.13 ± 5.10

4.51 ± 2.95

3.96 ± 2.95

 

G/G N = 434

172/262

26.52 ± 4.76

16.31 ± 5.29

7.88 ± 4.61

4.13 ± 3.10

4.52 ± 2.92

P value

  

 n.s.

0.010 a

 n.s.

0.016 a

 n.s.

rs2036373

G/G N = 2

1/1

32.30 ± 12.45

17.83 ± 2.53

8.00 ± 7.1

4.25 ± 3.18

2.00 ± 0.00

 

G/T N = 75

38/37

26.87 ± 4.42

16.50 ± 5.99

7.87 ± 4.8

4.87 ± 3.03

4.67 ± 3.09

 

T/T N = 811

313/498

26.43 ± 4.64

16.65 ± 5.01

7.92 ± 4.

4.32 ± 3.01

3.85 ± 2.79

P value

  

 n.s.

 n.s.

 n.s.

 n.s.

0.049 a

rs17366743

C/C N = 0

      
 

C/T N = 39

18/21

27.30 ± 3.27

14.96 ± 4.84

8.91 ± 5.72

4.77 ± 3.52

3.59 ± 2.58

 

T/T N = 855

339/516

26.43 ± 4.71

16.71 ± 5.12

7.88 ± 4.86

4.31 ± 2.98

3.92 ± 2.81

P value

  

 n.s.

0.036 a

 n.s.

 n.s.

 n.s.

  1. Data are presented as mean ± SD
  2. n.s. non-significant (P > 0.05)
  3. a P values (additive model of inheritance) were calculated using linear regression analysis, adjusted for age, gender and ln BMI