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Fig. 2 | Genes & Nutrition

Fig. 2

From: PPARα via HNF4α regulates the expression of genes encoding hepatic amino acid catabolizing enzymes to maintain metabolic homeostasis

Fig. 2

Lipid content in Ppara-null mice is altered by the DP/DCH ratio. Mice were fed diets containing 6/77, 20/63 or 50/33 % DP/DCH during 8 days and then were fasted for 16 h or refed for 3 h. a Histological analysis of liver sections stained with hematoxylin and eosin (H&E) and Oil Red O in mice after refeeding. b Heat map of genes related to FAO in the livers of WT versus Ppara-null (KO) mice after refeeding (n = 3–4). c Free fatty acids of Ppara-null and WT mice in fasted or d refeeding. White bars WT; black bars Ppara-null. Results represent mean ± SEM (n = 4–5)

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