Table 1 Genotype and minor allele frequencies for the MTHFR and MTR single-nucleotide polymorphisms (SNPs) in the MASTOS study

MTHFR 677C>T (rs1801133)

C/C

361

437

C/T

516

526

T/T

188

194

MAF^a

0.42

0.39

Hardy–Weinberg (P value)^b

0.10

MTHFR 1298A>C (rs1801131)

A/A

138

150

A/C

465

501

C/C

468

486

MAF^a

0.65

0.65

Hardy–Weinberg (P value)^b

0.24

MTR 2756A>G (rs1805087)

A/A

679

684

A/G

350

404

G/G

45

68

MAF^a

0.2

0.23

Hardy–Weinberg (P value)^b

0.41