Peripheral mononuclear blood cells contribute to the obesity-associated inflammatory state independently of glycemic status: involvement of the novel proinflammatory adipokines chemerin, chitinase-3-like protein 1, lipocalin-2 and osteopontin

Table 3 Univariate analysis of the correlations between gene expression levels of the analyzed inflammatory markers and anthropometric and biochemical variables

	mRNA LCN2		mRNA CHI3L1		mRNA SPP1		mRNA RARRES2
	r	P	r	P	r	P	r	P
Age	0.22	0.074	−0.01	0.993	0.23	0.061	0.04	0.699
BMI	0.65	<0.001	0.37	0.002	0.58	<0.001	0.42	<0.001
Body fat	0.66	<0.001	0.34	0.007	0.56	<0.001	0.43	0.008
Fasting glucose	0.20	0.166	0.01	0.991	−0.04	0.732	−0.04	0.973
Fasting insulin	0.48	<0.001	0.29	0.036	0.27	0.055	0.24	0.097
QUICKI	−0.60	<0.001	−0.38	0.007	−0.49	0.004	−0.35	0.015
LDL-cholesterol	0.37	0.015	0.28	0.059	0.33	0.029	0.44	0.003
HDL-cholesterol	−0.43	0.002	−0.22	0.136	−0.18	0.231	−0.31	0.041
Leptin	0.51	0.003	0.27	0.057	0.45	0.002	0.36	0.015
CRP	0.53	<0.001	0.27	0.071	0.43	0.003	0.10	0.523
Fibrinogen	0.52	<0.001	0.15	0.312	0.38	0.007	0.17	0.269
von Willebrand factor	0.27	0.078	0.29	0.048	0.39	0.008	0.28	0.066
AST	0.02	0.998	0.27	0.052	0.12	0.356	−0.10	0.482
ALT	0.26	0.072	0.32	0.017	0.23	0.094	0.06	0.656

Bold values denote statistically significant P values
ALT alanine aminotransferase, AST aspartate aminotransferase, BMI body mass index, CRP C-reactive protein, QUICKI quantitative insulin sensitivity check index

ISSN: 1865-3499