Table 2 Detailed overview of OR genes with damaging missense variants on chromosome 1q

28

1q23

OR10J1

T/C

rs35634161

M70T

0.983/0.017 (59/1)

0.981/0.019^c

13

OR10K2

T/G

rs79869455

L39R

0.983/0.017 (59/1)

0.990/0.010^b

11, 12, 13, 14, 16, 19, 21, 28, 30

OR10T2

G/A

rs61818749

C89Y

0.850/0.150 (51/9)

0.909/0.091^c

2, 4, 7, 8, 9, 11, 13, 14, 17, 18, 23, 26, 27, 30

OR10Z1

A/C

rs857685

N294T

0.733/0.267 (44/16)

0.764/0.236^c

1, 2, 3, 5, 6, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30

1q44

OR2AK2

G/A

rs4478844

V203 M

0.367/0.633 (22/38)

0.384/0.616^c

1, 4, 5, 6, 7, 9, 12, 13, 15, 16, 17, 19, 21, 23, 24, 26, 29

OR2G2

T/C

rs10925085

L167P

0.667/0.333 (40/20)

0.597/0.403^c

26

OR2G3

C/A

A237D

0.983/0.017 (59/1)

13

OR2M3

T/A

rs144171858

I289 N

0.983/0.017 (59/1)

0.998/0.002^a

1, 24

OR2M5

C/A

rs41304157

A237D

0.967/0.033 (58/2)

0.981/0.019^c

30

OR2T11

T/G

rs75010552

M203R

0.967/0.033 (58/2)

0.992/0.008^c

13

OR2T2

G/A

rs145665149

G234D

0.983/0.017 (59/1)

0.999/0.001^b

13

OR2T3

G/C

rs148805039

G21A

0.983/0.017 (59/1)

0.998/0.002^a

3, 4, 6, 7, 8, 9, 10, 11, 13, 17, 19, 21, 25, 26, 28, 29, 30

G/A

rs148025314

C132Y

0.817/0.183 (43/17)

0.811/0.189^a

8, 19, 25

T/C

rs148748995

F183S

0.950/0.050 (57/3)

0.997/0.003^a

1, 4, 12, 13, 14, 17, 19, 20, 21, 25, 26, 28, 29

OR2T6

T/G

rs954475

S243A

0.767/0.233 (46/14)

0.852/0.148^c

3, 4, 8, 30

OR2T34

G/A

rs147489167

C132Y

0.917/0.083 (55/5)

0.993/0.007^a

2, 4, 5, 8, 13, 14, 19, 25, 26, 30

T/C

rs150608839

F183S

0.834/0.166 (50/10)

0.896/0.104^a

2, 5, 6, 7, 8, 10, 14, 15, 16, 18, 26, 27, 28, 30

OR14C36

G/T

rs28545014

D231Y^##

0.700/0.300 (42/18)

0.431/0.569^c

3, 4, 6, 8, 10, 11, 22, 30

OR14I1

A/G

rs55871516

Y216C

0.867/0.133 (52/8)

0.868/0.132^c