Estrogen and n-3 polyunsaturated fatty acid supplementation have a synergistic hypotriglyceridemic effect in ovariectomized rats

Table 2 Dietary intake, body weight, and various organ weights

	0 % n-3	1 % n-3	2 % n-3	0 % n-3 + E₂	1 % n-3 + E₂	2 % n-3 + E₂
Dietary intake (g/day)	15.51 ± 0.21	15.52 ± 0.11	15.44 ± 0.08	14.24 ± 0.09*	14.27 ± 0.42*	14.44 ± 0.03*
Initial body weight (g)	94.50 ± 2.00	94.25 ± 2.95	94.75 ± 2.54	94.75 ± 2.21	94.75 ± 1.79	94.44 ± 2.00
Final body weight (g)	297.75 ± 3.32	300.25 ± 3.75	300.63 ± 6.96	261.00 ± 3.55*	263.31 ± 3.36*	263.63 ± 2.76*
Liver weight (g)	6.34 ± 0.12	6.61 ± 0.17	6.46 ± 0.21	6.48 ± 0.14	6.37 ± 0.07	6.53 ± 0.06
Skeletal muscle weight (g)	25.45 ± 0.85	25.76 ± 0.82	25.33 ± 0.88	24.86 ± 0.33	24.89 ± 0.23	24.75 ± 0.44
Kidney weight (g)	1.69 ± 0.02	1.65 ± 0.04	1.68 ± 0.02	1.70 ± 0.02	1.68 ± 0.02	1.72 ± 0.02
Visceral fat weight (g)	4.13 ± 0.18	4.68 ± 0.33	4.51 ± 0.29	2.81 ± 0.17*	2.80 ± 0.14*	2.71 ± 0.16*
Uterus weight (g)	0.09 ± 0.00	0.09 ± 0.00	0.09 ± 0.00	0.40 ± 0.01*	0.40 ± 0.01*	0.41 ± 0.01*

Values are mean ± SEM; 0, 1, and 2 % n-3, 0, 1, and 2 % EPA + DHA diet with corn oil injection; 0, 1, and 2 % n-3 +E₂, 0, 1 and 2 % EPA + DHA diet with 17β-estradiol-3-benzoate injection
* Values are significantly different (P < 0.05) between corn oil and E₂ injection for diets containing the same amount of n-3 PUFA

ISSN: 1865-3499