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Table 3 Serum lipid profile and hepatic lipid contents

From: Estrogen and n-3 polyunsaturated fatty acid supplementation have a synergistic hypotriglyceridemic effect in ovariectomized rats

 

0 % n-3

1 % n-3

2 % n-3

0 % n-3 + E2

1 % n-3 + E2

2 % n-3 + E2

Serum

 Triglyceride (mmol/L)

0.64 ± 0.02

0.57 ± 0.03†

0.49 ± 0.02†,††

0.57 ± 0.01*

0.49 ± 0.00†,*

0.44 ± 0.01†,††,*

 Total cholesterol (mmol/L)

2.68 ± 0.12

2.46 ± 0.04†

2.16 ± 0.05†,††

2.68 ± 0.07

2.41 ± 0.06†

2.13 ± 0.07†,††

 HDL cholesterol (mmol/L)

0.66 ± 0.03

0.68 ± 0.03

0.65 ± 0.02

1.05 ± 0.04*

1.06 ± 0.04*

1.06 ± 0.02*

 LDL cholesterol (mmol/L)

1.62 ± 0.10

1.38 ± 0.06†

1.10 ± 0.06†,††

1.54 ± 0.09

1.24 ± 0.02†

0.91 ± 0.04†,††

Liver

 Triglyceride (mg/g liver)

65.13 ± 4.39

55.48 ± 4.18†

45.86 ± 3.99†,††

25.15 ± 2.19*

15.02 ± 1.03†,*

14.22 ± 0.98†,*

 Total cholesterol (mg/g liver)

61.14 ± 1.13

56.78 ± 1.69†

53.82 ± 0.65†

51.08 ± 1.82*

45.70 ± 0.98†,*

44.46 ± 0.76†,*

  1. Values are mean ± SEM; 0, 1, and 2 % n-3, 0 % 1 %, and 2 % EPA + DHA diet with corn oil injection; 0, 1, and 2 % n-3 + E2, 0, 1 and 2 % EPA + DHA diet with 17β-estradiol-3-benzoate injection
  2. * Values are significantly different (P < 0.05) between corn oil and E2 injection for diets containing the same amount of n-3 PUFA
  3. †Values are significantly different (P < 0.05) among 0, 1, and 2 % n-3 within the corn oil- and E2-injected groups
  4. ††Values are significantly different (P < 0.05) between 1 % and 2 % n-3 within the corn oil- and E2-injected groups