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Table 3 Effects of MLE on plasma lipid profile and hepatic function in high-fat diet-induced obese mice

From: Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice

Group

Lipid profile

Hepatic function

TG (mg/dl)

TC (mg/dl)

HDL-C (mg/dl)

LDL-C (mg/dl)

AI

GOT (Karmen/ml)

GPT (Karmen/ml)

CON

69.98 ± 5.46a

109.14 ± 10.98a

69.59 ± 6.00ab

30.52 ± 4.26a

0.66 ± 0.03a

161.38 ± 27.05ab

24.77 ± 0.55a

HF

154.37 ± 14.51c

167.77 ± 9.29b

60.43 ± 4.79a

59.70 ± 5.17b

1.54 ± 0.32b

200.84 ± 31.17b

126.45 ± 18.13b

L

110.41 ± 11.03b

135.16 ± 13.08a

82.24 ± 8.11b

22.91 ± 7.71a

0.53 ± 0.12a

117.07 ± 15.50a

53.35 ± 11.67a

H

103.22 ± 1.86b

128.15 ± 7.41a

81.05 ± 2.36ab

25.05 ± 5.51a

0.58 ± 0.08a

125.10 ± 8.29a

46.13 ± 21.88a

  1. Values are mean ± SEM and n = 6 for each group. The significance was tested by ANOVA with Duncan’s test for multiple comparisons. Values with the same superscript letter are not significantly different (P < 0.05)
  2. CON, normal control diet-fed mice; HF, high-fat diet-fed control; L, low-dose mulberry leaf extract (133 mg/kg)-treated high-fat diet-fed mice; H, high-dose mulberry leaf extract (666 mg/kg)-treated high-fat diet-fed mice