Fig. 5

Cell proliferation (relative cell number) of non-transfected and miR-106b mimic or miR-135a mimic-transfected LT97 cells after 24-h (a), 48-h (b) and 72-h (c) incubation with 2, 4, 10 mM butyrate and 3.3 µM TSA (trichostatin A). Results represent fold changes (fc) on the basis of a medium control (MC = 100 %). All results were significantly different compared to MC (P ≤ 0.001). Significant differences: ^# P ≤ 0.05, ^## P ≤ 0.01 between transfected and non-transfected and ^a,b,c,d P ≤ 0.05 between different concentrations of butyrate and TSA (represented by different letters); Student’s t test (mean + SD, n = 3 independent experiments with 6 technical replicates, respectively)