| Incident type 2 diabetesa | FPG (mmol/L)b | FPI (pmol/L)b | HbA1C (%)b | ||||
---|---|---|---|---|---|---|---|---|
 | HR (95 % CI) | P value | Beta (SE) | P value | Beta (SE) | P value | Beta (SE) | P value |
TCF7L2 rs7903146 | 1.33 (1.25–1.40) | 1 × 10−23 | 0.04 (0.02) | 0.03 | 0.16 (1.05) | 0.82 | 0.02 (0.01) | 0.04 |
TCF7L2 rs12255372 | 1.24 (1.17–1.31) | 9 × 10−14 | 0.03 (0.02) | 0.15 | −0.73 (1.07) | 0.79 | 0.02 (0.01) | 0.07 |
HHEX rs1111875 | 1.06 (1.01–1.12) | 0.03 | −0.02 (0.02) | 0.20 | −3.07 (0.99) | 0.016 | 0.01 (0.01) | 0.31 |
HNF1A rs7957197 | 1.12 (1.05–1.20) | 0.001 | 0.04 (0.02) | 0.04 | 1.11 (1.23) | 0.54 | 0.01 (0.01) | 0.30 |
NOTCH2 rs10923931 | 0.99 (0.91–1.09) | 0.90 | 0.04 (0.03) | 0.19 | −0.14 (1.73) | 0.69 | 0.02 (0.02) | 0.35 |
TLE4 rs13292136 | 1.03 (0.94–1.12) | 0.60 | −7 × 10−05 (0.03) | 1.00 | 1.71 (1.72) | 0.40 | 0.02 (0.02) | 0.30 |
ZBED3 rs4457053 | 1.01 (0.96–1.08) | 0.64 | 0.01 (0.02) | 0.44 | −1.41 (1.14) | 0.22 | 0.02 (0.01) | 0.04 |
PPARG rs1801282 | 1.08 (1.00–1.16) | 0.051 | 0.03 (0.02) | 0.24 | 1.16 (1.38) | 0.42 | −0.002 (0.01) | 0.88 |
PPARG rs13081389 | 1.00 (0.91–1.11) | 0.97 | 0.03 (0.03) | 0.35 | 1.67 (1.79) | 0.33 | 0.01 (0.02) | 0.68 |