Table 6 List of gene ontologies (biological processes) significantly regulated by PFJ

GO:0010903

Negative regulation of very-low-density lipoprotein particle remodelling

3

100.0000

26.2353

0.0000

GO:0060192

Negative regulation of lipase activity

4

40.0000

19.0387

0.0000

GO:0033700

Phospholipid efflux

4

33.3333

17.3429

0.0000

GO:0060416

Response to growth hormone stimulus

4

30.7692

16.6448

0.0000

GO:0032488

Cdc42 protein signal transduction

2

50.0000

15.0814

0.0000

GO:0046461

Neutral lipid catabolic process

3

33.3333

15.0179

0.0000

GO:0042157

Lipoprotein metabolic process

5

20.0000

14.8938

0.0000

GO:0007494

Midgut development

3

30.0000

14.2268

0.0000

GO:0048261

Negative regulation of receptor-mediated endocytosis

2

40.0000

13.4602

0.0000

GO:0010915

Regulation of very-low-density lipoprotein particle clearance

2

40.0000

13.4602

0.0000

GO:0071825

Protein-lipid complex subunit organisation

4

19.0476

12.9842

0.0000

GO:0015918

Sterol transport

5

14.2857

12.4800

0.0000

GO:0050995

Negative regulation of lipid catabolic process

3

23.0769

12.4241

0.0005

GO:0030300

Regulation of intestinal cholesterol absorption

2

33.3333

12.2609

0.0000

GO:0034381

Plasma lipoprotein particle clearance

3

21.4286

11.9549

0.0000

GO:0008203

Cholesterol metabolic process

7

9.5890

11.9276

0.0000

GO:0034367

Macromolecular complex remodelling

3

20.0000

11.5328

0.0000

GO:0010873

Positive regulation of cholesterol esterification

2

28.5714

11.3268

0.0000

GO:0018904

Organic ether metabolic process

7

8.6420

11.2675

0.0000

GO:0071941

Nitrogen cycle metabolic process

2

22.2222

9.9459

0.0000

GO:0051055

Negative regulation of lipid biosynthetic process

3

13.6364

9.4265

0.0000

GO:0071320

Cellular response to cyclic adenosine monophosphate

2

20.0000

9.4149

0.0005

GO:0042632

Cholesterol homeostasis

4

10.0000

9.2153

0.0000

GO:0071396

Cellular response to lipid

3

13.0435

9.2059

0.0005

GO:0071383

Cellular response to steroid hormone stimulus

5

6.4935

8.1091

0.0000

GO:0006720

Isoprenoid metabolic process

4

7.0175

7.5752

0.0000

GO:0050817

Coagulation

4

5.8824

6.8498

0.0000

GO:0001101

Response to acid

4

5.7971

6.7922

0.0005

GO:0010243

Response to organic nitrogen

5

4.7170

6.7315

0.0000

GO:0044272

Sulphur compound biosynthetic process

3

7.3171

6.7133

0.0015

GO:0017144

Drug metabolic process

2

10.5263

6.6960

0.0045

GO:0033762

Response to glucagon stimulus

3

6.9767

6.5356

0.0005

GO:0044106

Cellular amine metabolic process

9

2.7692

6.4744

0.0000

GO:0043436

Oxoacid metabolic process

12

2.1053

6.1883

0.0000

GO:0033574

Response to testosterone stimulus

2

9.0909

6.1811

0.0030

GO:0009636

Response to toxin

4

4.7619

6.0507

0.0010

GO:0031100

Organ regeneration

3

5.8824

5.9287

0.0010

GO:0042743

Hydrogen peroxide metabolic process

2

8.3333

5.8913

0.0045

GO:0031667

Response to nutrient levels

7

2.7237

5.6322

0.0000

GO:0051262

Protein tetramerisation

3

5.3571

5.6146

0.0020

GO:0031330

Negative regulation of cellular catabolic process

2

7.1429

5.4051

0.0060

GO:0030193

Regulation of blood coagulation

2

6.8966

5.2990

0.0060

GO:0010043

Response to zinc ion

2

6.8966

5.2990

0.0050

GO:0031647

Regulation of protein stability

3

4.8387

5.2867

0.0020

GO:0051384

Response to glucocorticoid stimulus

4

3.3898

4.9035

0.0010

GO:0007623

Circadian rhythm

3

4.2254

4.8711

0.0040

GO:0055114

Oxidation-reduction process

11

1.6129

4.7935

0.0000

GO:0071375

Cellular response to peptide hormone stimulus

4

3.1008

4.6273

0.0035

GO:0006725

Cellular aromatic compound metabolic process

4

2.9851

4.5123

0.0015

GO:0033013

Tetrapyrrole metabolic process

2

5.1282

4.4651

0.0070

GO:0051186

Cofactor metabolic process

5

2.4510

4.4123

0.0005

GO:0033555

Multicellular organismal response to stress

2

4.3478

4.0441

0.0110

GO:0044262

Cellular carbohydrate metabolic process

6

1.8127

3.8583

0.0045

GO:0061061

Muscle structure development

2

3.8462

3.7493

0.0190

GO:0042445

Hormone metabolic process

3

2.7027

3.6494

0.0100

GO:0042493

Response to drug

5

1.8116

3.5138

0.0045

GO:0006730

One-carbon metabolic process

4

1.9802

3.3655

0.0125

GO:0007626

Locomotory behaviour

3

2.3810

3.3384

0.0125

GO:0014070

Response to organic cyclic compound

4

1.9417

3.3146

0.0065

GO:0048513

Organ development

9

1.1704

3.1890

0.0050

GO:0009607

Response to biotic stimulus

6

1.4458

3.1796

0.0090

GO:0009611

Response to wounding

5

1.6026

3.1729

0.0120

GO:0009791

Post-embryonic development

2

2.7778

3.0325

0.0375

GO:0006414

Translational elongation

2

2.6316

2.9216

0.0485

GO:0010466

Negative regulation of peptidase activity

3

1.9868

2.9171

0.0325

GO:0050679

Positive regulation of epithelial cell proliferation

2

2.4096

2.7455

0.0480

GO:0035335

Peptidyl-tyrosine dephosphorylation

2

2.3529

2.6988

0.0380

GO:0034284

Response to monosaccharide stimulus

2

2.3529

2.6988

0.0490

GO:0032989

Cellular component morphogenesis

4

1.4652

2.6156

0.0285

GO:0009967

Positive regulation of signal transduction

5

1.1876

2.3859

0.0305

GO:0032006

Regulation of mTORsignalling cascade

2

12.5000

6.1613

0.0040

GO:0031113

Regulation of microtubule polymerisation

2

11.1111

5.7727

0.0070

GO:0001702

Gastrulation with mouth forming second

2

9.0909

5.1559

0.0075

GO:0045216

Cell-cell junction organisation

2

5.2632

3.7231

0.0245

GO:0042632

Cholesterol homeostasis

2

5.0000

3.6045

0.0235

GO:0006793

Phosphorus metabolic process

14

1.4433

3.5098

0.0015

GO:0031214

Biomineral tissue development

2

4.5455

3.3902

0.0280

GO:0002263

Cell activation involved in immune response

2

4.5455

3.3902

0.0320

GO:0042475

Odontogenesis of dentine-containing tooth

2

4.4444

3.3408

0.0315

GO:0032259

Methylation

4

2.5157

3.1405

0.0145

GO:0030155

Regulation of cell adhesion

4

2.4096

3.0318

0.0160

GO:0050790

Regulation of catalytic activity

15

1.2490

3.0295

0.0080

GO:0010243

Response to organic nitrogen

3

2.8302

2.9800

0.0270

GO:0001933

Negative regulation of protein phosphorylation

2

3.6364

2.9179

0.0460

GO:0071841

Cellular component organisation or biogenesis at cellular level

18

1.0508

2.5596

0.0140

GO:0019219

Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

21

0.9620

2.3612

0.0210

GO:0008219

Cell death

7

1.3514

2.2489

0.0340