Skip to main content

Advertisement

Table 2 Relative expression of genes (fold change, Chinese vs. Indian) with known variants between rhesus monkeys of different origin in the prefrontal cortex (PFC), cerebellum (CER), and striatum (STR) (n = 3 per group)

From: Brain xanthophyll content and exploratory gene expression analysis: subspecies differences in rhesus macaque

  Fold change-PFC p value Fold change-CER p value Fold change-STR p value
CCL5 1.07 0.98 1.01 0.99 1.15 0.94
CXCL12 1.45 0.19 1.18 0.61 3.22 0.00058
XCL1 1.43 0.42 0.89 0.77 3.57 0.11
CCR4 1.50 0.67 1.27 0.72 1.19 0.79
CCR1 1.94 0.02 1.46 0.21 1.57 0.07
IL2RA 2.04 0.50 1.89 0.58 1.00 0.98
CD74 2.11 0.0001 1.44 0.09 2.52 0.0000043
CD4 3.69 0.0000001 1.66 0.008 3.59 0.0000006
CD44 −1.08 0.81 −1.12 0.31 1.27 0.38
TLR5 1.06 0.83 −1.20 0.63 1.02 0.94
LTBR −1.52 0.02 −1.28 0.22 −1.06 0.80
FAS 1.27 0.58 1.24 0.57 −1.39 0.43
MAOA 1.06 0.72 1.03 0.89 1.04 0.86
BCHE 1.13 0.15 1.43 0.12 −1.01 0.99
NOS1 1.06 0.82 1.24 0.25 1.57 0.05
NPY 1.00 0.99 −10.0 0.05 1.18 0.36
PYY 1.08 0.92 1.92 0.65 3.04 0.41
SLC5A7 1.56 0.19 1.67 0.19 1.01 0.95
SLC6A4 1.67 0.67 −3.23 0.27 −1.75 0.69
SNCA 1.21 0.10 1.08 0.63 1.41 0.04
INHBB −1.11 0.68 −1.08 0.82 1.13 0.68
SIRT1 1.13 0.51 1.08 0.64 1.23 0.34
HTATSF1 1.10 0.35 1.03 0.82 1.13 0.41
STAR −1.52 0.18 −1.30 0.49 −1.04 0.91
ADRBK2 1.21 0.19 1.11 0.49 1.52 0.08
ITGA4 −1.10 0.74 1.01 0.99 1.80 0.32
SASH1 1.13 0.35 1.21 0.31 1.30 0.12
  1. Fold change calculated by dividing fragments per kilobase of transcript per million mapped reads (FPKM) Chinese origin by FPKM Indian origin. Genes in italics showed a significant difference in expression in at last one brain region. Genes bold were selected for RT-PCR analysis