Fig. 3

Changes in serum glucose concentrations during the insulin tolerance test (ITT). Control, OVX rats fed a high-fat diet (HFD) with 1% dextrin; CFM, OVX rats fed an HFD with 1% lyophilized cauliflower mushroom; LFE, OVX rats fed an HFD with 0.1% L. fermentum plus 1% dextrin; CFLF, OVX rats fed an HFD with 1% CFM plus 0.1% L. fermentum; positive-control, OVX rats fed an HFD with 1% dextrin plus 30 μg/kg body weight 17β-estradiol. ITT was conducted with intraperitoneal injection of 0.75 IU insulin/kg body weight and measured serum glucose concentrations in blood collected from the tail every 15 min for 90 min. Changes of serum glucose concentrations were shown during ITT (a). The average of the area under the curve (AUC) of glucose during the first part (0–45 min) and second part (45–90 min) of ITT (b) was given. Each dot and bar represents the mean ± SD (n = 12). Asterisk indicates significantly different among the treatments of OVX rats at p < 0.05. Different letters represent a significant difference in Tukey test at p < 0.05