Table 6 Selected biological processes identified in DAVID for differentially expressed target genes (DET)
No. | Biological processes | Number of identified genes | List of genes | FDR |
|---|---|---|---|---|
1 | Muscle organ development | 17 | six1, tiparp, acta1, cav3, cxcl10, col19a1, cxadr, foxp1, fxr1, mapk14, rarb, sgcd, zfand5, tcf12, tagln2, tpm1, zfpm2 | 8.3E−03 |
2 | Modification-dependent protein catabolic process | 27 | ube2g1, rnf217, edem3, edem1, otub2, cul3, fbxl19, rnf125, cyld, map1lc3b, rnf11, hectd1, ubr3, ube2h, mid1, hltf, trim63, march3, fem1c, dcun1d1, nedd4, rnf2, trim32, usp47, rnf138, cul4b, usp25 | 1.4E−01 |
3 | Muscle cell differentiation | 11 | tbx18, acta1, cav3, cxadr, foxp1,neo1, ntf3, rarb, sort1, syne1, tpm1 | 2.5E−01 |
4 | Proteolysis involved in cellular catabolic process | 27 | ube2g1, rnf217, edem3, edem1, otub2, cul3, fbxl19, rnf125, cyld, map1lc3b, rnf11, hectd1, ubr3, ube2h, mid1, hltf, trim63, march3, fem1c, dcun1d1, nedd4, rnf2, trim32, usp47, rnf138, cul4b, | 2.8E−01 |
5 | Muscle tissue development | 11 | six1, tpm1, tiparp, acta1, col19a1,cxadrp2, foxp1, mapk14, rarb, zfand5, zfpm2 | 3.3E−01 |
6 | Protein catabolic process | 27 | ube2g1, rnf217, edem3, edem1, otub2, cul3, fbxl19, rnf125, cyld, map1lc3b, rnf11, hectd1, ubr3, ube2h, mid1, hltf, trim63, march3, fem1c, dcun1d1, nedd4, rnf2, trim32, usp47, rnf138, cul4b, usp25 | 4.8E−01 |
7 | Proteolysis | 37 | ube2g1, rnf217, edem3, otub2, edem1, rnf125, cul3, fbxl19, cyld, ece1, map1lc3b, rnf11, dpp8, nsf, hectd1, capn6, nrip3, capn7, mmp19, ubr3, ube2h, mid1, hltf, trim63, march3, fem1c, dcun1d1, nedd4, rnf2, trim32, usp47, rnf138, tep1, nln, cul4b, usp25, adamts3 | 1.6E−00 |
8 | Regulation of apoptosis | 29 | ier3, cadm1, mcl1, tlr4, sgms1, mcf2l, slc11a2, cul3, map3k7, bdnf, tiam2, sos2, ngfrap1, faim, rarb, ip6k2, fgd4, traf3, rarg, ntf3, arhgef12, pla2g4a, eya1, tnfsf13b, dusp1, ets1, igf2r, sort1, jak2 | 4.5E−00 |
9 | Positive regulation of cellular biosynthetic process | 25 | tlr4, abca1, rarb, fam129a, znf423, rarg, epas1, ntf3, npr1, itga2, creb5, arntl, mecom, wwtr1, pla2g4a, ncoa1, sp1, ets1, mapk14, six1, pdgfra, jak2, zfpm2, smarca1, klf4 | 8.3E−00 |
10 | Positive regulation of cell proliferation | 16 | nampt, fgf7, itga2, vash2, foxp1, cxcl10, cul3, cd47, vegfc, pla2g4a, tnfsf13b, pdgfra, jak2, mab21l1, tbx18, pggt1b | 2.7E−01 |
11 | Positive regulation of inflammatory response | 4 | jak2, itga2, pla2g4a, tlr4 | 3.1E−01 |