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Fig. 3 | Genes & Nutrition

Fig. 3

From: Betaine reduces β-amyloid-induced paralysis through activation of cystathionine-β-synthase in an Alzheimer model of Caenorhabditis elegans

Fig. 3

The glutathione synthesis is not involved in the paralysis reducing effects of betaine. Under cbs-1 RNAi, betaine was no longer able to reduce Hcy level significantly (a) nor to diminish paralysis (b). Knockdown of gcs-1, encoding the key enzyme for glutathione synthesis, did neither affect paralysis nor prevent the paralysis reducing effects of betaine (c). **p < 0.01, ***p < 0.001 versus vector control

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Genes & Nutrition

ISSN: 1865-3499

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