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Fig. 2 | Genes & Nutrition

Fig. 2

From: High nutrient intake during the early postnatal period accelerates skeletal muscle fiber growth and maturity in intrauterine growth-restricted pigs

Fig. 2

Effects of the level of nutrient intake on mRNA abundance of growth-related genes in psoas major muscle of pigs with different birth weight. Values are means, with their standard errors represented by vertical bars (n = 6 for each group). Mean values with different letters (a, b, c) were significantly different between four groups (P < 0.05). , IUGR/ANI; , NBW/ANI; , IUGR/HNI; , NBW/HNI. ANI, adequate nutrient intake; HNI, high nutrient intake; IUGR, intrauterine growth restriction; NBW, normal birth weight; IGF1R, insulin-like growth factor 1 receptor; GHR, growth hormone receptor; Akt, protein kinase B; mTOR, mammalian target of rapamycin; RPS6, ribosomal protein S6; eIF4E, eukaryotic translation initiation factor 4E; eIF4EBP1, eukaryotic translation initiation factor 4E binding protein 1. For IGF1, IGF1R, mTOR, RPS6, and eIF4E, there was a significant effect of body weight (P < 0.05). For IGF1, IGF1R, Akt, mTOR, RPS6, and eIF4E, there was a significant effect of nutrient intake (P < 0.05). Furthermore, there was a significant interaction between body weight and nutrient intake on the mRNA abundance of GHR and RPS6 (P < 0.05)

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