Table 3 Genes with the most altered expression (log2 ratio > |0.25|) in responders compared to non-responders to omega-3 supplementation
Gene | Probe ID | Difference in log ratio* | 95% CI | P value | Biological function/process |
|---|---|---|---|---|---|
LINC01000 | ILMN_3234967 | − 0.47 | (− 0.76 to − 0.19) | 0.003 | Unknown |
TGFBR3 | ILMN_1784287 | − 0.40 | (− 0.71 to − 0.09) | 0.01 | Growth factor and cytokine signaling |
CCDC88C | ILMN_3248352 | − 0.37 | (− 0.74 to 0.0) | 0.05 | Wnt signaling |
SDF4 | ILMN_2378257 | − 0.33 | (− 0.66 to − 0.01) | 0.05 | Ca2+ binding |
PKN1 | ILMN_2367710 | − 0.31 | (− 0.6 to − 0.02) | 0.04 | Signal transduction in apoptosis |
SNORD33 | ILMN_1682354 | − 0.30 | (− 0.55 to − 0.05) | 0.02 | Small nucleolar RNA |
NBPF10 | ILMN_2155719 | − 0.29 | (− 0.54 to − 0.04) | 0.02 | Unknown |
HNRNPL | ILMN_2389582 | − 0.28 | (− 0.48 to − 0.09) | 0.007 | mRNA processing |
CYFIP2 | ILMN_2354478 | − 0.28 | (− 0.53 to − 0.03) | 0.03 | T cell adhesion |
PRRC2A | ILMN_2408179 | − 0.28 | (− 0.55 to 0.0) | 0.05 | Associated with IDDM and RA development |
RFFL | ILMN_1753819 | − 0.28 | (− 0.4 to − 0.15) | 0.0002 | Apoptosis |
FYN | ILMN_2380801 | − 0.26 | (− 0.49 to − 0.03) | 0.03 | Proliferation |
GPKOW | ILMN_1684197 | − 0.26 | (− 0.49 to − 0.02) | 0.04 | mRNA processing |
ZNF683 | ILMN_1678238 | − 0.25 | (− 0.5 to − 0.01) | 0.04 | T cell differentiation |
SNN | ILMN_1788251 | 0.27 | (0.04 to 0.51) | 0.03 | Regulation of growth and apoptosis |
RPL7 | ILMN_1815292 | 0.30 | (0.01 to 0.58) | 0.04 | Ribosomal protein |
FTH1 | ILMN_1696911 | 0.32 | (0.05 to 0.59) | 0.02 | Iron storage |
RPS3A | ILMN_1679025 | 0.34 | (0.03 to 0.66) | 0.04 | Ribosomal protein |