Table 3 Hub genes identified in the blue module
Probe ID | Gene (Chr, accession number) | GS TC | p value GS | MM | p value MM | Potential causal relationships of the hub genes1 |
|---|---|---|---|---|---|---|
ID_2350019 | FEZ1 (Chr11, NM_ 022549) | 0.31 | 0.032 | − 0.81 | 4.55 × 10−12 | Unknown |
ID_6940768 | MYBPC3 (Chr11, NM_000256) | 0.34 | 0.019 | − 0.80 | 1.06 × 10−11 | Likely regulator |
ID_1440754 | OPRL1 (Chr20, NM_000913) | 0.30 | 0.037 | − 0.70 | 3.76 × 10−8 | Likely regulator |
ID_5870341 | LOC642691 (Chr1, withdrawn) | 0.30 | 0.040 | − 0.69 | 5.85 × 10−8 | Unknown |
ID_3780017 | SIRPB1 (Chr20, NM_006065) | 0.40 | 0.0049 | − 0.68 | 1.01 × 10−7 | Likely regulated |
ID_110719 | SLC16A3 (Chr17, NM_004207) | 0.30 | 0.037 | − 0.62 | 2.45 × 10−6 | Likely regulator |
ID_2120152 | SLC4A1 (Chr17, NM_000342) | 0.31 | 0.030 | − 0.60 | 6.55 × 10−6 | Likely regulated |
ID_2630739 | HS.154948 | − 0.42 | 0.0032 | 0.60 | 6.37 × 10−6 | Likely regulated |
ID_6040072 | GPR89C (Chr1, NM_001097616) | − 0.46 | 0.0012 | 0.61 | 4.10 × 10−6 | Likely regulated |
ID_5810070 | PSMD6 (Chr3, NM_014814) | − 0.36 | 0.012 | 0.62 | 3.19 × 10−6 | Likely regulated |
ID_7000735 | RANBP1 (Chr22, NM_002882) | − 0.38 | 0.0072 | 0.62 | 2.63 × 10−6 | Likely regulated |
ID_6200437 | AP3M1 (Chr10, NM_207012) | − 0.47 | 0.00076 | 0.62 | 2.35 × 10−6 | Likely regulated |
ID_4670703 | SMIM13 (Chr6, XM_927609) | − 0.35 | 0.013 | 0.62 | 2.29 × 10−6 | Likely regulated |
ID_1510270 | SIRT5 (Chr6, NM_012241) | − 0.29 | 0.042 | 0.63 | 1.48 × 10−6 | Likely regulator |
ID_3890632 | DNM1L (Chr12, NM_012063) | − 0.32 | 0.028 | 0.63 | 1.46 × 10−6 | Unknown |
ID_4810292 | CR2 (Chr1, NM_001877) | − 0.42 | 0.0030 | 0.64 | 1.03 × 10−6 | Likely regulated |
ID_2810246 | LBH (Chr2, NM_030915) | − 0.46 | 0.0011 | 0.64 | 9.22 × 10−7 | Likely regulated |
ID_10209 | HNRNPA1 (Chr12, NM_031157) | − 0.53 | 8.78 × 10−5 | 0.64 | 7.83 × 10−7 | Likely regulator |
ID_1090367 | BIVM (Chr13, NM_017693) | − 0.38 | 0.0085 | 0.66 | 3.64 × 10−7 | Likely regulated |
ID_5560465 | NOP56 (Chr20, NM_006392) | − 0.38 | 0.0079 | 0.67 | 1.70 × 10−7 | Likely regulated |
ID_1990154 | PTMAP12 (Chr9, XM_001126659) | − 0.31 | 0.035 | 0.67 | 1.51 × 10−7 | Unknown |
ID_4010097 | FBXO5 (Chr6, NM_012177) | − 0.42 | 0.0027 | 0.68 | 1.37 × 10−7 | Likely regulated |
ID_7100367 | HS.571502 | − 0.39 | 0.0057 | 0.69 | 7.78 × 10−8 | Likely regulated |
ID_4850133 | SNRPN (Chr15, NM_022806) | − 0.37 | 0.0096 | 0.69 | 6.75 × 10−8 | Likely regulated |
ID_7160719 | CCT7 (Chr2, NM_006429) | − 0.47 | 0.00069 | 0.69 | 4.71 × 10−8 | Likely regulated |
ID_5560504 | TIAL1 (Chr10, NM_003252) | − 0.29 | 0.042 | 0.70 | 2.85 × 10−8 | Unknown |
ID_6840747 | SLC25A4 (Chr4, NM_001151) | − 0.32 | 0.028 | 0.72 | 7.82 × 10−9 | Unknown |
ID_6900079 | PCNA (Chr20, NM_182649) | − 0.42 | 0.0032 | 0.74 | 2.27 × 10−9 | Likely regulated |
ID_7150132 | PNN (Chr14, NM_002687) | − 0.31 | 0.031 | 0.74 | 2.23 × 10−9 | Unknown |
ID_3170189 | S100PBP (Chr1, NM_022753) | − 0.30 | 0.038 | 0.76 | 4.91 × 10−10 | Unknown |
ID_110059 | UBA5 (Chr3, NM_024818) | − 0.39 | 0.0061 | 0.80 | 1.12 × 10−11 | Likely regulated |
ID_4260093 | TUT4 (Chr1, NM_001009882) | − 0.46 | 0.00096 | 0.81 | 2.10 × 10−12 | Likely regulated |