Table 4 Frequency of VDR, RXRα and RXRγ variants in EUR, EAS and AFR groups

 rs886441

60 (2356)

0.18 (0.16–0.21)

0.05 (0.02–0.07)

0.41 (0.38–0.43)

1.66e–27

0.88

EUR ≠ AFR ≠ EAS

 rs2283342

60 (2356)

0.26 (0.22–0.29)

0.49 (0.43–0.55)

0.00 (− 0.04–0.05)

6.70e–19

0.76

EUR ≠ AFR ≠ EAS

 rs2107301

60 (2356)

0.32 (0.29–0.35)

0.67 (0.63–0.70)

0.13 (0.10–0.16)

1.91e–30

0.91

EUR ≠ AFR ≠ EAS

 rs4334089

60 (2356)

0.73 (0.68–0.77)

0.57 (0.52–0.61)

0.35 (0.30–0.39)

1.95e–16

0.71

EUR ≠ AFR ≠ EAS

 rs4516035

60 (2355)

0.43 (0.41–0.45)

0.03^a (0.00–0.05)

0.03^a (0.01–0.05)

3.68e–34

0.93

EUR ≠ AFR and EAS

 rs1805343

45 (1853)

0.66^a (0.63–0.69)

0.65^a (0.63–0.68)

0.17 (0.14–0.19)

6.81e–29

0.95

AFR ≠ EUR and EAS

 rs1805352

44 (1822)

0.69^a (0.66–0.72)

0.75^a (0.72–0.78)

0.26 (0.23–0.29)

2.82e–27

0.95

AFR ≠ EUR and EAS

 rs10881582

46 (1881)

0.74^a (0.71–0.77)

0.81^a (0.78–0.83)

0.25 (0.22–0.28)

1.04e–30

0.96

AFR ≠ EUR and EAS

 rs3118571

45 (1854)

0.65^a (0.62–0.68)

0.69^a (0.66–0.72)

0.12 (0.09–0.15)

9.27e–30

0.96

AFR ≠ EUR and EAS

 rs3818740

45 (1853)

0.40^a,b,c (0.29–0.52)

0.43^a,b,c (0.32–0.53)

0.59^a,b,c (0.48–0.70)

3.85e–02

0.10

-

 rs731516

45 (1852)

1.00^a (0.98–1.02)

1.00^a (0.98–1.02)

0.59 (0.57–0.61)

1.20e–31

0.96

AFR ≠ EUR and EAS

 rs7040434

45 (1854)

0.00^a (− 0.01–0.02)

0.00^a (− 0.01–0.01)

0.53 (0.52–0.54)

4.26e–44

0.99

AFR ≠ EUR and EAS

 rs283695

60 (2356)

0.44 (0.40–0.47)

0.77^a (0.73–0.80)

0.85^a (0.82–0.89)

8.45e–25

0.85

EUR ≠ AFR and EAS

 rs12069160

60 (2356)

0.94^a (0.92–0.96)

0.65 (0.62–0.67)

0.92^a (0.90–0.95)

2.69e–24

0.85

EAS ≠ AFR and EUR

 rs10800098

60 (2345)

0.05^a (0.02–0.08)

0.33 (0.30–0.36)

0.03^a (0.00–0.06)

8.40e–21

0.80

EAS ≠ AFR and EUR

 rs10489745

60 (2343)

0.09^a (0.07–0.12)

0.42 (0.40–0.45)

0.03^a (0.01–0.05)

3.57e–33

0.92

EAS ≠ AFR and EUR