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Table 2 Effect of flaxseed oil supplementation on fatty acids status of erythrocytes

From: Effect of flaxseed oil supplementation on the erythrocyte membrane fatty acid composition and endocannabinoid system modulation in patients with coronary artery disease: a double-blind randomized controlled trial

Variable

Flaxseed oil (n = 21)

Placebo (n = 19)

MD (95% CI), P value

LA (%)

 Before

14.53 (6.22)

15.59 (8.48)

1.32 (− 4.26 to 6.90), 0.632a

 After

9.68 (3.25)

12.10 (3.94)

2.89 (0.07 to 5.72), 0.045b

MD (95% CI), P valuec

− 4.84 (− 9.16 to − 0.53), 0.031

− 3.49 (− 7.18 to 0.19), 0.062

 

AA (%)

 Before

13.59 (5.64)

11.59 (6.87)

− 1.21 (− 6.07 to 3.65), 0.613a

 After

9.56 (1.40)

8.75 (1.56)

− 1.06 (− 2.47 to 0.36), 0.135b

MD (95% CI), P valuec

− 4.03 (− 7.46 to − 0.60), 0.026

− 2.84 (− 6.76 to 1.07), 0.143

 

ALA (%)

 Before

0.20 (0.12)

0.21 (0.11)

0.01 (− 0.07 to 0.10), 0.679a

 After

0.56 (0.24)

0.22 (0.10)

− 0.35 (− 0.51 to − 0.20), < 0.001b

MD (95% CI), P valuec

0.37 (0.23 to 0.51), < 0.001

0.004 (− 0.08 to 0.09), 0.925

 

EPA (%)

 Before

1.15 (0.60)

1.08 (0.87)

− 0.28 (− 0.84 to 0.27), 0.301a

 After

1.06 (0.72)

0.87 (0.50)

− 0.29 (− 0.96 to 0.37), 0.364b

MD (95% CI), P valuec

− 0.09 (− 0.51 to 0.32), 0.612

− 0.21 (− 0.65 to 0.22), 0.305

 

DHA (%)

 Before

1.43 (0.87)

1.24 (0.76)

− 0.20 (− 0.83 to 0.43), 0.520a

 After

1.36 (0.44)

1.29 (0.46)

− 0.08 (− 0.52 to 0.36), 0.704b

MD (95% CI), P valuec

− 0.07 (− 0.80 to 0.65), 0.822

0.05 (− 0.35 to 0.45), 0.796

 
  1. Values are expressed as mean (SD)
  2. LA linoleic acid, AA arachidonic acid, ALA α-linolenic acid, EPA eicosapentaenoic acid, DHA docosahexaenoic acid, MD mean difference
  3. aIndependent samples t-test
  4. bAdjusted for baseline values, weight differences, and energy and fat intake changes using the analysis of covariance (ANCOVA) test
  5. cPaired-samples t-test