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Fig. 4 | Genes & Nutrition

Fig. 4

From: Alteration of gut microbiota affects expression of adiponectin and resistin through modifying DNA methylation in high-fat diet-induced obese mice

Fig. 4

Effects of antibiotics on the mRNA expression of genes associated with fatty acid metabolism and DNA methyltransferase in the adipose tissue. The mouse experimental procedure was the same as in Fig. 1. a, b Fat synthesis-associated genes, acetyl-CoA carboxylase 1 (Acc1), and fatty acid synthase (Fas). c–f Fat hydrolysis and oxidation-associated genes, cell death-inducing DNA fragmentation factor-alpha-like effector A (Cidea), adipose triglyceride lipase (Atgl), peroxisome proliferator-activated receptor-alpha (PPAR-α), peroxisome proliferator-activated receptor-γ coactivator1 alpha (Pgc-1α). g–i DNA methyltransferases 1, 3a, and 3b (DNMT1, DNMT3a, and DNMT3b). n = 10 in each group. Data are means ± SD. *Compared to the NC group, P < 0.05; #compared to the DIO group, P < 0.05

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