Table 2 Serum folate level (median (25th–75th) and DNA methylation status (n (%)) in the three groups
Variables | Control (n = 200) | EPL (n = 200) | ESCC (n = 200) | p value |
|---|---|---|---|---|
Serum folate (μg/L) | 29.14 (24.43–36.24) | 25.72 (21.29–29.47)a | 24.79 (20.73–29.85)a | < 0.001* |
No. of p16 methylation | 70 (35.0%) | 92 (46.0%)b | 126 (63.0%)b | < 0.05†|
No. of p53 methylation | 74 (36.5%) | 84 (42.0%) | 113 (56.5%)b | < 0.05†|