Table 7 Association between foods rich in folate with p53 methylation status and the risk of EPL and ESCC
Food intake frequency | EPL [OR (95% CI)a, p for interaction] | ESCC [OR (95% CI)a, p for interaction] | ||||||
|---|---|---|---|---|---|---|---|---|
p53U | p value | p53M | p value | p53U | p value | p53M | p value | |
Spinach | ||||||||
 Never | 1.00 (reference) | - | 0.39 (0.07–2.13) | 0.277 | 1.00 (reference) | - | 1.54 (0.44–5.32) | 0.499 |
 Less than once per week | 1.04 (0.36–3.08) | 0.937 | 1.01 (0.33–3.13) | 0.980 | 0.28 (0.10–0.77) | 0.014 | 0.51 (0.19–1.42) | 0.199 |
 Once per week or more | 0.71 (0.24–2.04) | 0.520 | 0.85 (0.28–2.52) | 0.765 | 0.27 (0.11–0.71) | 0.008 | 0.61 (0.23–1.59) | 0.311 |
Chinese cabbage | ||||||||
 Never | 1.00 (reference) | - | 1.16 (0.73–1.83) | 0.527 | 1.00 (reference) | - | 2.19 (1.36–3.51) | 0.001 |
 Less than once per week | 0.71 (0.23–2.20) | 0.544 | 0.83 (0.20–3.42) | 0.796 | 2.26 (0.84–6.07) | 0.106 | 3.95 (1.22–12.84) | 0.022 |
 Once per week or more | 0.23 (0.11–0.49) | < 0.001 | 0.29 (0.11–0.78) | 0.014 | 0.40 (0.19–0.85) | 0.017 | 1.01 (0.46–2.23) | 0.985 |
Livers | ||||||||
 Never | 1.00 (reference) | - | 1.19 (0.78–1.83) | 0.426 | 1.00 (reference) | - | 2.10 (1.36–3.24) | 0.001 |
 Less than once per week | 0.31 (0.13–0.73) | 0.007 | 0.63 (0.10–3.84) | 0.614 | 0.71 (0.34–1.49) | 0.369 | 4.38 (1.16–16.50) | 0.029 |
 Once per week or more | 0.94 (0.26–3.35) | 0.925 | 0.24 (0.03–2.14) | 0.199 | 0.26 (0.03–2.30) | 0.227 | 0.33 (0.04–3.00) | 0.324 |
Beans | ||||||||
 Never | 1.00 (reference) | - | 0.63 (0.31–1.27) | 0.193 | 1.00 (reference) | - | 1.44 (0.72–2.89) | 0.301 |
 Less than once per week | 1.06 (0.54–2.10) | 0.862 | 1.74 (0.69–4.34) | 0.239 | 0.88 (0.41–1.89) | 0.747 | 2.51(0.98–6.42) | 0.056 |
 Once per week or more | 0.51 (0.26–0.99) | 0.048 | 0.94 (0.44–2.03) | 0.873 | 0.67 (0.33–1.35) | 0.263 | 2.26(1.06–4.82) | 0.462 |