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Fig. 6 | Genes & Nutrition

Fig. 6

From: TCONS_00230836 silencing restores stearic acid-induced β cell dysfunction through alleviating endoplasmic reticulum stress rather than apoptosis

Fig. 6

Knockdown of the lncRNA TCONS_00230836 apparently relieved stearic acid-induced ER stress-related proteins in β-TC6 cells. a Effect of the lncRNA TCONS_00230836 Smart Silencer on the expression of Phospho-PERK and Phospho-eIF2α proteins in stearic acid-treated β-TC6 cells. b Western blot analysis showed the alteration of ATF-6 and IRE1α protein levels after transfection of the TCONS_00230836 Smart Silencer in β-TC6 cells exposed to stearic acid. NS not significant, SA stearic acid, si-lnc836 transfection of the Smart Silencer for the lncRNA TCONS_00230836. *p < 0.05 versus the control group; ^p < 0.05 versus the stearic acid group. n = 3 independent cell cultures in each group

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Genes & Nutrition

ISSN: 1865-3499

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