From: A systematic review to identify biomarkers of intake for fermented food products
Fermented food(s) | Discriminant compounds/candidate biomarker levela | ||||
---|---|---|---|---|---|
Food-level | Food group-levelb | Fermentation-dependent | |||
Wine | • Tartaric acid/tartrate • Resveratrol and metabolites (trans-piceid, glucuronides and sulfates) | • (Epi)catechin and metabolites (also see cocoa, coffee, tea) | • Ethanol • Ethyl glucuronide • Ethyl sulfate | • Mannitol • Gallic acid | |
Beer | • (Iso)xanthohumol • Iso-alpha-acids (isohumulones) • 8-Prenylnaringenin | • Alkylresorcinols and metabolites (3,5-dihydroxybenzoic acid, DHPPA, C17:0 to C21:0 ratio) • Benzoxazinoids and related compounds (2-hydroxyl-1,4-benzoxazin-3-one, hydroxylated phenylacetamides and derivatives, HHPAA glucuronide and sulfate) | • Ferulic acid, dihydroferulic acid, and derivatives | • 2-Ethyl malate | |
Bread | • 2,4-Dihydroxybutanoic acid* • 2,8-Dihydroxyquinoline glucuronide* | • Methionine | |||
Cocoa | • None identified | • Caffeine and metabolites (theophylline, 1-methylxanthine, 3-methylxanthine, 7-methylxanthine, paraxanthine, theobromine, AAMU, AMMU) • 1-, 3-, or 7-Methyluric acid, 1,3-, 1,7-, or 3,7-dimethyluric acid, 1,3,7-trimethyluric acid • Chlorogenic acid, caffeic acids, quinic acids • Nicotinic acid, hydroxynicotinic acid • (Epi)catechin, (epi)catechin glucuronide and metabolites (3-hydroxyhippurate, MHPV, MHPV sulfate, glucuronide, 4-hydroxy-5-(3,4-dihydroxyphenyl) valeric acid, 4-hydroxy-5-(hydroxyphenyl) valeric acid sulfate, DHPV glucuronide, sulfoglucuronide) | • Acetate/acetic acid | ||
Coffee | • Trigonelline • N-methylpyridinium • Cyclo(isoleucyl-prolyl) • Atractyligenin glucuronide • 2-Furoylglycine • 4-Ethylguaiacol • 4-Vinylguaiacol | ||||
Teac | • C-linked dihydrochalcone and flavanone glucosides | • Theabrownins • Gallic acid | |||
Soyc | • None identified | • Pinitol • Isoflavones (daidzein, genistein, glycitein), glycoside-enriched | • Aglycone-enriched isoflavones and certain 4′ and 7′ isoflavone metabolites • Threonine, Tryptophan, Tyrosine, Valine • Vitamin B12 • Indole-3-lactic acid | • 4-Methylspinacemine • Menaquinone-7 (vitamin K2) | |
Cheese | • Isovalerylglutamic acid • Isovalerylglycine • Triglylglycine • Isobutyrylglycine | • Pentadecanoic acid (C15:0) • Heptadecanoic acid (C17:0) • 10Z-Heptadecenoic acid (C17:1) • Myristoyl-sphingomyelin SM(d18:1/14:0) • Lactose • Galactitol • Galactonate • Galactono-1,5-lactone • Galactose | • 3-Phenyllactic acid • Methionine | ||
• Lactic acid | |||||
Yoghurt | • None identified | • Indole-3-lactic acid, indole-3-acetaldehyde, indole-3-propionic acid |