An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals—the CODAM study

Table 2 WBC profile for the study participants

	Insulin sensitive (N=92)	Insulin resistant (N=65)	p	FDR-p
B cells (%)	9 ± 3	8 ± 4	0.113	0.306
NK-cells (%)	11 ± 6	10 ± 6	0.299	0.418
CD4T cells (%)	28 ± 14	26 ± 9	0.131	0.306
CD8T cells (%)	10 ± 10	9 ± 9	0.697	0.814
Monocytes (%)	12 ± 4	14 ± 7	0.002	0.016
Neutrophils (%)	26 ± 16	29 ± 16	0.246	0.418
Eosinophils (%)	0 ± 0	0 ± 0	0.947	0.947

EpiDISH was used to estimate the WBC profile from the DNA methylation data. Data are median ± MAD (median absolute deviation). P values were calculated with the Wilcoxon rank-sum test. Multiplicity correction was performed by applying the Benjamini-Hochberg method to control the false discovery rate. The median eosinophil composition of 0% means very low abundance

ISSN: 1865-3499