Interactions between red and processed meat consumption and APOA5 gene variants associated with the incidence of metabolic syndrome in Korean adults

Table 4 Interactions between red and processed meat consumption (serving/day) and APOA5 rs662799 polymorphism with the incidence of metabolic syndrome in Korean adults

	Total (serving/day)			p interaction¹	Men (serving/day)			p interaction¹	Women (serving/day)			p interaction¹
	Tertile 1	Tertile 2	Tertile 3	p interaction¹	Tertile 1	Tertile 2	Tertile 3	p interaction¹	Tertile 1	Tertile 2	Tertile 3	p interaction¹
Median	0.12	0.34	0.76		0.17	0.41	0.85		0.09	0.27	0.63
Ranges	0.00–0.22	0.22–0.50	0.50–6.13		0.00–0.27	0.27–0.56	0.56–6.13		0.00–0.17	0.17–0.42	0.42–5.96
Cases (n)/total (n)	541/1089	519/1088	524/1089		268/574	267/577	279/575		277/512	250/515	243/513
rs662799
AA	1.00 (reference)	1.11 (0.93–1.33)	1.20 (0.99–1.45)	< 0.001	1.00 (reference)	1.02 (0.79–1.33)	0.96 (0.73–1.27)	0.056	1.00 (reference)	1.38* (1.08–1.77)	1.16 (0.89–1.51)	0.002
AG + GG	1.36* (1.15–1.61)	1.47* (1.24–1.76)	1.42* (1.18–1.72)	< 0.001	1.27 (1.00–1.62)	1.21 (0.94–1.56)	1.24 (0.94–1.62)	0.056	1.47* (1.16–1.87)	1.48* (1.15–1.90)	1.70* (1.30–2.22)	0.002

Data are presented as adjusted hazard ratios (HRs) and 95% confidence intervals (CIs). The total models were adjusted for residential area, age, sex, educational level, household income, drinking status, smoking status, physical activity, body mass index (BMI), energy intake (kcal/day), and intake of white meat (g/day), fish (g/day), vegetable (g/day), fruit (g/day), and dairy (g/day). The male and female models were adjusted for residential area, age, educational level, household income, drinking status, smoking status, physical activity, BMI, energy intake (kcal/day), and intake of white meat (g/day), fish (g/day), vegetable (g/day), fruit (g/day), and dairy (g/day)
¹p interaction was obtained by genotype and red and processed meat consumption as categorical variables and adjusted for covariates
*p value < 0.05

ISSN: 1865-3499