Altered macronutrient composition and genetics influence the complex transcriptional network associated with adiposity in the Collaborative Cross

Table 5 Distribution of significant enrichment terms across modules

	GO biological process 2018	GO molecular function 2018	Jensen diseases	KEGG 2019 mouse	Total
Brown	296	25	18	80	419
Turquoise	289	55	1	49	394
Greenyellow	25	11	18	16	70
Red	37	2	3	24	66
Purple	34	2	2	14	52
Yellow	27	11	2	6	46
Magenta	35	4	2	2	43
Black	18	17	3	0	38
Green	24	5	0	8	37
Blue	22	3	0	8	33
Salmon	2	0	0	0	2
Pink	0	1	0	0	1
Tan	0	0	0	0	0

In Enrichr analysis, genes assigned to each module were used to determine whether modules were significantly enriched for functional terms, pathways, or diseases (enrichment terms). Modules varied widely in terms of the number of enrichments for each category, from no enrichments at all (tan) to 419 total enrichments (brown)

ISSN: 1865-3499