Table 3 MR analysis results of exposure (including vitamin D intake and serum vitamin D) and functional dyspepsia (FD)
Exposure | MR Method | No.SNP | β | SE | OR(95%CI) | P | Ajusted-P |
|---|---|---|---|---|---|---|---|
Vitamin D intake | MR Egger | 53 | − 0.051104 | 0.1045778 | 0.9501(0.7740,1.1663) | 0.62716 | − |
Weighted median | 0.1229543 | 0.1184692 | 1.1308(0.8965,1.4264) | 0.29933 | − | ||
IVW (fixed effects) | 0.0641415 | 0.076215 | 1.0662(0.9182,1.2380) | 0.40001 | − | ||
Maximum likelihood | 0.0643745 | 0.0763783 | 1.0664(0.9182, 1.2387) | 0.39931 | 0.53333 | ||
Penalized-weighted median | 0.136949 | 0.1203150 | 1.1467(0.9058,1.4517) | 0.25501 | − | ||
MR-PRESSO | 0.0656 | 0.07594 | 1.0678(0.9558,1.1928) | 0.39134 | − | ||
25-hydroxyvitaminD | MR Egger | 92 | − 0.17933 | 0.136803 | 0.8358( 0.6392,1.093) | 0.1932 | − |
Weighted median | − 0.087774 | 0.144605 | 0.915(0.6927, 1.211) | 0.5439 | − | ||
IVW (fixed effects) | − 0.03722 | 0.092349 | 0.9634(0.8039,1.155) | 0.68693 | 0.6869 | ||
Maximum likelihood | 0.036860 | 0.092580 | 0.9638(0.8039, 1.156) | 0.69052 | − | ||
Penalized-weighted median | − 0.08717 | 0.14474 | 0.9165(0.6797,1.236) | 0.54701 | − | ||
MR-PRESSO | − 0.0325 | 0.0840 | 0.9680(0.8665,1.0813) | 0.6996 | − |