Fig. 4
From: Causal relationship between dietary salt intake and dementia risk: Mendelian randomization study
Leave-one-out plot in the MR study. Leave-one-out plot for sensitivity analysis of single SNP effect on dietary salt intake to dementia results: A Alzheimer’s disease, B Vascular dementia, C Lewy body dementia, D dementia. Leave-one-out plot using IVW method by sequentially re-evaluating the causal estimate after discarding one SNP at a time, which helps determine whether the overall effect is driven by the specific genetic variant. The black point denotes the causal effect estimate of dietary salt intake on dementia after discarding a certain SNP, and the black line signifies the 95% CI of estimate. The red point symbolizes the causal effect estimate of dietary salt intake on dementia with the valid SNPs, and the red line indicates the 95% CI of the estimate. Abbreviations: CI, confidence interval; SNP, number of single-nucleotide polymorphism