Table 4 Influences of Haptoglobin (Hp), MnSOD, CAT, GPx-1, ACE, GSTM1, GSTT1, CK NcoI, CK TaqI, CRP G1059C, MTHFR C677T and MTHFR A1298C genes’ polymorphisms on the leukogram before and after pequi-oil supplementation

Hp

 1F-1F

6,425.00 ± 290.78

6,850.00 ± 548.05

2,313.75 ± 197.11

2,359.00 ± 299.70

3,435.25 ± 268.34

3,704.00 ± 488.19

13.25 ± 13.25

11.38 ± 11.38

79.13 ± 16.48

91.88 ± 11.19

149.00 ± 22.29

112.13 ± 19.04

434.63 ± 68.44

571.63 ± 66.68

 1F-1S

7,487.50 ± 1,291.93

7,000.00 ± 853.77

1,923.75 ± 193.56

2,297.63 ± 276.28

4,740.13 ± 1,176.15

3,909.50 ± 607.49

101.00 ± 64.76

26.50 ± 26.50

83.00 ± 14.49

79.50 ± 13.40

101.25 ± 23.42

134.38 ± 47.93

539.50 ± 93.29

549.88 ± 94.59

 1S-1S

7,994.12 ± 715.15

7,764.71 ± 605.61

2,719.56 ± 209.79

2,586.89 ± 184.12

4,470.89 ± 596.70

4,343.22 ± 465.01

28.22 ± 19.38

26.35 ± 16.53

74.17 ± 12.39

89.22 ± 12.95

175.56 ± 32.29

173.44 ± 36.23

524.50 ± 52.14

556.72 ± 49.65

 1F-2

7,515.00 ± 414.49

7,690.00 ± 329.03

2,840.05 ± 199.83

2,651.90 ± 169.33

3,914.45 ± 265.02

4,024.95 ± 301.57

3.32 ± 3.32

5.11 ± 5.11

88.45 ± 12.73

105.30 ± 10.36

158.55 ± 31.11

152.05 ± 29.82

491.60 ± 40.33

586.10 ± 47.22

 1S-2

7,103.12 ± 419.06

7,090.63 ± 356.60

2,599.75 ± 206.66

2,656.38 ± 237.66

3,788.91 ± 267.41

3,644.50 ± 218.58

37.81 ± 18.06

43.25 ± 20.76

77.03 ± 8.51

93.22 ± 7.83

129.69 ± 18.90

155.41 ± 15.49*

462.44 ± 36.09

495.66 ± 31.21

 2-2

7,696.87 ± 311.91

7,771.88 ± 316.01

2,885.69 ± 164.48

2,743.87 ± 169.69

4,021.81 ± 229.42

4,156.53 ± 234.81

11.72 ± 6.90

26.28 ± 15.44

100.56 ± 9.21

111.13 ± 8.73

149.75 ± 20.97

165.34 ± 26.74

524.69 ± 46.44

569.59 ± 39.20

 P values

0.433

0.437

0.070

0.810

0.728

0.517

0.314

0.857

0.373

0.276

0.625

0.684

0.816

0.607

MnSOD

 Val/Val

7,305.26 ± 508.09

7,136.84 ± 423.87

2,871.68 ± 304.69

2,597.79 ± 210.58

3,711.79 ± 270.98

3,670.47 ± 326.61

8.72 ± 6.03

15.78 ± 15.78

75.16 ± 9.94

87.16 ± 8.91

176.84 ± 33.90

183.74 ± 25.56

457.11 ± 50.54

500.42 ± 49.65

 Val/Ala

7,484.95 ± 237.47

7,523.66 ± 206.72

2,644.79 ± 93.08

2,628.18 ± 107.11

4,076.53 ± 188.75

4,042.41 ± 151.86

30.39 ± 9.44

29.99 ± 9.24

87.04 ± 5.51

101.46 ± 5.06

141.76 ± 11.36

149.90 ± 13.50

503.16 ± 23.01

557.33 ± 21.27*

 Ala/Ala

7,240.00 ± 1,027.91

7,380.00 ± 673.35

2,403.00 ± 242.8

2,651.20 ± 286.97

4,078.60 ± 839.11

3,898.40 ± 458.03

11.20 ± 11.20

0.00 ± 0.00

94.80 ± 10.50

85.80 ± 10.32

118.00 ± 42.3

163.40 ± 37.81

534.40 ± 102.24

581.20 ± 79.12

 P values

0.908

0.823

0.793

0.924

0.865

0.675

0.803

0.442

0.298

0.346

0.764

0.178

0.567

0.413

CAT

 AA

7,280.00 ± 558.83

6,920.00 ± 425.85

2,739.43 ± 230.87

2,728.10 ± 209.69

3,856.81 ± 472.24

3,473.38 ± 261.02

13.43 ± 13.43

24.81 ± 20.49

77.90 ± 11.97

75.19 ± 7.82

139.24 ± 18.77

180.71 ± 29.16**,^≠

482.86 ± 45.05

551.43 ± 44.30

 AT

7,540.00 ± 309.01

7,728.00 ± 283.23

2,799.60 ± 141.04

2,746.08 ± 157.72

3,975.84 ± 224.25

4,037.00 ± 220.21

26.34 ± 11.78

27.62 ± 12.62

84.94 ± 7.33

113.96 ± 6.87**,^a,≠,*,^c

151.48 ± 18.82

145.54 ± 18.38

490.68 ± 28.67

563.22 ± 27.78*,^≠

 TT

7,414.89 ± 332.48

7,391.49 ± 274.95

2,503.81 ± 129.93

2,448.28 ± 127.73

4,134.60 ± 249.53

4,136.74 ± 204.45

31.98 ± 13.55

26.02 ± 11.17

89.38 ± 7.14

92.45 ± 6.49

144.19 ± 16.11

155.89 ± 17.48

510.21 ± 36.45

533.23 ± 32.21

 P values

0.757

0.412

0.407

0.525

0.393

0.151

0.311

0.917

0.758

0.004

0.954

0.556

0.942

0.805

GPx-1

 Pro/Pro

7,787.93 ± 324.14

7,484.48 ± 272.35

2,689.93 ± 131.51

2,516.60 ± 128.63*,^≠

4,312.79 ± 266.69

4,168.45 ± 196.70

39.59 ± 13.99

32.38 ± 11.54

90.53 ± 6.19

102.28 ± 7.12

138.02 ± 15.27

129.81 ± 13.62

512.07 ± 31.61

529.48 ± 24.85

 Pro/Leu

7,030.43 ± 286.62

7,373.91 ± 263.72

2,619.77 ± 143.84

2,692.94 ± 143.41

3,706.91 ± 188.07

3,806.43 ± 195.90

7.09 ± 3.17

25.98 ± 13.24

77.57 ± 7.95

94.28 ± 5.89*

160.64 ± 18.16

184.49 ± 22.07

480.04 ± 29.17

582.83 ± 32.73*,^≠

 Leu/Leu

7,384.62 ± 622.63

7,607.69 ± 558.67

2,772.46 ± 221.73

2,856.31 ± 323.78

3,826.46 ± 446.38

3,734.31 ± 433.76

36.75 ± 28.07

0.00 ± 0.00

91.31 ± 15.08

96.85 ± 9.09

132.31 ± 22.70

169.15 ± 27.42

491.69 ± 61.19*^,≠

515.38 ± 58.35

 P values

0.427

0.981

0.678

0.454

0.588

0.712

0.307

0.196

0.294

0.918

0.639

0.109

0.791

0.355

ACE

 DD

7,036.59 ± 356.98

7,319.51 ± 328.45

2,686.63 ± 157.06

2,667.78 ± 170.95

3,607.46 ± 240.84

3,794.80 ± 228.24

29.61 ± 13.42

35.52 ± 15.41

77.85 ± 7.34

92.05 ± 8.44

131.80 ± 14.50

131.90 ± 11.56

503.29 ± 36.44

562.56 ± 33.02

 ID

8,013.79 ± 301.45*,^a,c

7,632.76 ± 266.94

2,761.20 ± 120.09

2,657.81 ± 123.92

4,461.86 ± 253.69*^,a

4,136.25 ± 186.21

28.93 ± 12.17

19.05 ± 10.08

91.68 ± 6.93

103.07 ± 5.48

157.92 ± 17.25

179.22 ± 20.77

505.51 ± 29.13

560.44 ± 28.43

 II

6,544.44 ± 374.97

7,188.89 ± 269.21

2,340.22 ± 239.79

2,415.17 ± 226.57

3,497.50 ± 213.75

3,866.22 ± 349.23

9.89 ± 5.74

30.39 ± 18.08

82.39 ± 12.27

98.17 ± 10.63

141.89 ± 25.58

134.28 ± 18.46

455.22 ± 45.57

481.78 ± 32.80

 P values

0.009

0.482

0.188

0.625

0.028

0.360

0.774

0.512

0.287

0.352

0.891

0.576

0.577

0.345

GSTM1

 Null

7,306.49 ± 235.12

7,254.55 ± 208.22

2,735.84 ± 107.97

2,661.48 ± 115.81

3,853.82 ± 180.95

3,758.60 ± 142.72

18.24 ± 8.04

14.75 ± 8.35

82.04 ± 5.54

93.56 ± 5.00

135.21 ± 12.70

153.01 ± 13.27*,^≠

481.71 ± 24.97

553.49 ± 24.08**,^≠

 Non-null

7,712.50 ± 412.00

7,840.00 ± 335.69

2,549.44 ± 157.54

2,554.37 ± 152.86

4,326.02 ± 307.62

4,385.51 ± 264.55

41.07 ± 15.98

48.80 ± 15.72**,^a

91.88 ± 8.62

107.76 ± 8.03

167.41 ± 19.26

161.39 ± 22.51

525.90 ± 35.38

541.07 ± 31.07

 P values

0.627

0.276

0.268

0.543

0.232

0.092

0.077

0.003

0.367

0.153

0.102

0.966

0.247

0.828

GSTT1

 Null

8,482.35 ± 680.41

8,176.47 ± 552.77

2,970.29 ± 236.03

2,957.88 ± 195.32

4,511.65 ± 601.57

4,132.41 ± 460.59

6.24 ± 6.24

27.59 ± 21.49

100.12 ± 12.43

97.65 ± 7.70

218.76 ± 37.75

201.12 ± 33.01

651.76 ± 44.99

577.47 ± 48.18*,^≠

 Non-null

7,269.00 ± 212.09

7,332.00 ± 186.69

2,620.71 ± 95.92

2,568.11 ± 101.73*,^a

3,934.78 ± 157.17

3,950.17 ± 135.82

29.64 ± 8.89

26.30 ± 8.42

82.99 ± 5.05

98.63 ± 4.89

134.22 ± 10.38*,^a

148.32 ± 12.29*,^a

471.03 ± 21.63**,^a

544.42 ± 20.71**,^≠

 P Values

0.068

0.106

0.141

0.038

0.280

0.696

0.224

0.989

0.138

0.646

0.014

0.047

0.001

0.476

CK NcoI

 AA

7,337.29 ± 256.20

7,222.03 ± 233.48

2,663.32 ± 118.60

2,493.18 ± 115.56*,^≠

3,904.80 ± 178.46

3,926.12 ± 189.84

32.19 ± 11.64

36.68 ± 13.30

89.42 ± 6.84

94.27 ± 6.13

151.63 ± 13.04

155.70 ± 14.87

504.23 ± 30.06

527.20 ± 25.19

 AG

7,634.62 ± 363.81

7,671.15 ± 293.73

2,727.71 ± 146.35

2,773.42 ± 154.12

4,164.98 ± 295.52

3,996.40 ± 202.09

20.25 ± 11.12

17.82 ± 8.71

80.98 ± 6.63

104.15 ± 6.57*

146.19 ± 18.94

161.17 ± 19.94

484.15 ± 28.76

554.10 ± 29.57*^,≠

 GG

6,866.67 ± 644.29

7,866.67 ± 742.37

2,257.83 ± 262.59

2,642.33 ± 393.94

3,874.00 ± 462.32

4,306.33 ± 509.29

19.67 ± 12.70

0.00 ± 0.00

84.67 ± 25.48

91.67 ± 14.85

95.83 ± 17.64

112.67 ± 20.94

537.33 ± 106.28

726.33 ± 80.91

 P values

0.777

0.490

0.570

0.581

0.994

0.761

0.198

0.437

0.688

0.748

0.299

0.826

0.922

0.094

CK TaqI

 1-1

7,272.73 ± 564.74

7,081.82 ± 602.69

2,666.27 ± 256.58

2,288.09 ± 229.55

4,021.91 ± 525.48

4,095.00 ± 592.83

7.91 ± 7.91

17.09 ± 11.47

66.45 ± 16.36

97.36 ± 13.93

94.45 ± 18.88

92.09 ± 15.60

406.18 ± 60.78

492.18 ± 51.26

 1-2

7,284.21 ± 279.22

7,335.09 ± 223.92

2,658.65 ± 124.93

2,600.11 ± 120.46

3,849.95 ± 216.42

3,873.40 ± 178.49

23.18 ± 11.43

23.21 ± 11.14

87.58 ± 6.17

95.77 ± 5.66

140.67 ± 14.55

150.67 ± 15.99

513.60 ± 23.92

536.18 ± 25.51

 2-2

7,671.43 ± 359.75

7,677.55 ± 315.25

2,686.30 ± 146.77

2,725.76 ± 160.63

4,208.46 ± 262.99

4,067.78 ± 205.00

33.92 ± 12.55

32.35 ± 13.25

87.22 ± 7.79

101.84 ± 7.36

164.36 ± 18.26

175.96 ± 19.74

498.22 ± 37.33

576.54 ± 32.13**,^≠

 P values

0.809

0.822

0.983

0.534

0.538

0.676

0.284

0.64

0.508

0.919

0.244

0.138

0.308

0.402

CRP G1059C

 GG

7,349.04 ± 225.92

7,257.69 ± 183.85

2,626.70 ± 95.98

2,556.44 ± 92.16

3,976.72 ± 174.77

3,874.71 ± 139.61

28.91 ± 8.59

27.36 ± 8.63

86.35 ± 5.00

97.85 ± 4.68

142.18 ± 10.72

151.23 ± 11.39

488.79 ± 21.44

526.35 ± 18.48

 GC

8,215.38 ± 488.70

9,030.77 ± 507.30**,^a,*^,≠

3,029.46 ± 217.56

3,172.08 ± 357.89

4,350.38 ± 335.73

4,797.92 ± 373.79*,^a,≠

4.85 ± 4.85

19.62 ± 13.72

78.23 ± 13.83

103.69 ± 10.63

180.46 ± 44.49

193.85 ± 52.30

563.92 ± 65.40

733.54 ± 69.46**,^a, *,^≠

 P values

0.092

0.003

0.079

0.096

0.173

0.020

0.351

0.757

0.692

0.484

0.594

0.674

0.173

0.004

MTHFR C677T

 CC

7,201.79 ± 352.16

7,155.36 ± 249.82

2,592.72 ± 127.15

2,580.26 ± 130.98

3,941.67 ± 281.28

3,796.54 ± 183.41

27.58 ± 9.12

19.51 ± 8.28

78.79 ± 6.69

95.70 ± 5.67*^,≠

120.11 ± 13.46

137.16 ± 17.79

445.26 ± 32.54

512.04 ± 26.05

 CT

7,597.83 ± 276.69

7,784.78 ± 303.59

2,645.91 ± 144.50

2,636.72 ± 148.85

4,101.87 ± 199.01

4,245.48 ± 227.81

31.52 ± 15.92

40.07 ± 16.77

92.13 ± 7.65

98.91 ± 7.96

176.26 ± 18.90*^,a

171.61 ± 16.08*,^a

545.30 ± 26.25

585.04 ± 31.33

 TT

7,886.67 ± 462.38

7,560.00 ± 464.64

3,046.00 ± 244.37

2,753.27 ± 277.07

4,050.00 ± 289.17

3,834.87 ± 339.58

3.43 ± 3.43

11.29 ± 11.29

90.33 ± 12.86

107.80 ± 10.17

154.73 ± 29.35

179.13 ± 36.43*,^a,≠

546.00 ± 55.65

580.33 ± 54.72

 P values

0.129

0.347

0.235

0.932

0.172

0.386

0.339

0.791

0.401

0.481

0.038

0.029

0.018

0.394

MTHFR A1298C

 AA

7,512.86 ± 278.82

7,625.71 ± 241.07

2,713.39 ± 109.73

2,746.48 ± 118.22

4,039.68 ± 230.33

4,030.17 ± 180.08

29.75 ± 10.28

20.54 ± 8.21

76.96 ± 5.87

99.90 ± 6.08*

145.48 ± 13.49

164.86 ± 16.04

512.66 ± 28.33

566.37 ± 25.67

 AC

7,175.56 ± 263.14

7,093.33 ± 252.39

2,520.11 ± 134.50

2,348.73 ± 130.06*,^a,c

3,919.56 ± 184.62

3,883.69 ± 200.39

18.11 ± 11.56

34.36 ± 15.80

96.33 ± 7.62

94.84 ± 5.97

148.02 ± 18.46

144.49 ± 16.90

460.69 ± 27.20

516.60 ± 27.83

 CC

11,150.00 ± 4,950.00

9,600.00 ± 2,700.00

4,565.50 ± 1,713.50

4,485.00 ± 1,173.00

5,457.00 ± 2,915.00

4,155.00 ± 1,257.00

80.50 ± 80.50

61.50 ± 61.50

142.50 ± 18.50

130.50 ± 7.50

142.50 ± 18.50

96.00 ± 27.00

762.00 ± 204.00

672.00 ± 189.00

 P values

0.715

0.255

0.167

0.024

0.944

0.880

0.241

0.279

0.038

0.363

0.898

0.542

0.149

0.456