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  1. Monoamine oxidase A (MAOA) gene polymorphisms resulting in high and low transcription rates are associated with individual differences in reward efficacy and response inhibition. Iron deficiency (ID) is the mo...

    Authors: Mari Golub and Casey Hogrefe
    Citation: Genes & Nutrition 2014 9:381
  2. Alterations in trace element homeostasis could be involved in the pathology of dementia, and in particular of Alzheimer’s disease (AD). Zinc is a structural or functional component of many proteins, being invo...

    Authors: Johnathan R. Nuttall and Patricia I. Oteiza
    Citation: Genes & Nutrition 2013 9:379
  3. Nutrition research, like most biomedical disciplines, adopted and often uses experimental approaches based on Beadle and Tatum’s one gene—one polypeptide hypothesis, thereby reducing biological processes to s...

    Authors: Jim Kaput, Ben van Ommen, Bas Kremer, Corrado Priami, Jacqueline Pontes Monteiro, Melissa Morine, Fre Pepping, Zoey Diaz, Michael Fenech, Yiwu He, Ruud Albers, Christian A. Drevon, Chris T. Evelo, Robert E. W. Hancock, Carel IJsselmuiden, L. H. Lumey…
    Citation: Genes & Nutrition 2013 9:378
  4. Nutrition in early life is a determinant of lifelong physiological and metabolic function. Diseases that are associated with ageing may, therefore, have their antecedents in maternal nutrition during pregnanc...

    Authors: Zoe C. Daniel, Asli Akyol, Sarah McMullen and Simon C. Langley-Evans
    Citation: Genes & Nutrition 2013 9:365
  5. Moderate maternal calorie restriction during lactation protects rat offspring against obesity development in adulthood, due to an improved ability to handle and store excess dietary fuel. We used this model to...

    Authors: J. Konieczna, J. Sánchez, E. M. van Schothorst, J. M. Torrens, A. Bunschoten, M. Palou, C. Picó, J. Keijer and A. Palou
    Citation: Genes & Nutrition 2013 9:366
  6. Memory deficits are common during aging, but little is known about the impact of environmental and genetic variables on memory. The genes SLC30A3 and SEP15 are, respectively, responsible for transporting zinc and...

    Authors: Tatiane Jacobsen da Rocha, Cláudia Justin Blehm, Daiani Pires Bamberg, Tainá Ludmila Ramos Fonseca, Luciana Alves Tisser, Alcyr Alves de Oliveira Junior, Fabiana Michelsen de Andrade and Marilu Fiegenbaum
    Citation: Genes & Nutrition 2013 9:377
  7. Metabolites derived from the polyunsaturated fatty acids (PUFA) may modulate the mesenchymal stromal cell (MSC) differentiation. Such cells can differentiate into different cellular types, including adipocytes...

    Authors: Antonio Casado-Díaz, Carlos Ferreiro-Vera, Feliciano Priego-Capote, Gabriel Dorado, María Dolores Luque-de-Castro and José Manuel Quesada-Gómez
    Citation: Genes & Nutrition 2013 9:375
  8. Quercetin exhibits a wide range of biological functions. The first aim of the present work was to analyze the effects of quercetin on fat accumulation in adipose tissue and glycemic control in rats. Any poten...

    Authors: N. Arias, M. T. Macarulla, L. Aguirre, M. G. Martínez-Castaño and M. P. Portillo
    Citation: Genes & Nutrition 2013 9:361
  9. Oleuropein, the major phenolic compound found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Herein, we chara...

    Authors: Michaela Svobodova, Ioanna Andreadou, Alexios-Leandros Skaltsounis, Jan Kopecky and Pavel Flachs
    Citation: Genes & Nutrition 2013 9:376
  10. Dietary restriction (DR) increases life span, health span and resistance to stress in a wide range of organisms. Work from a large number of laboratories has revealed evolutionarily conserved mechanisms that m...

    Authors: Andreas Hanno Ludewig, Maja Klapper and Frank Döring
    Citation: Genes & Nutrition 2013 9:363
  11. Demyelination is a pathological process characterized by the loss of myelin around axons. In the central nervous system, oligodendroglial damage and demyelination are common pathological features characterizin...

    Authors: Ana M. Adamo
    Citation: Genes & Nutrition 2013 9:360
  12. Cellular polarity concerns the spatial asymmetric organization of cellular components and structures. Such organization is important not only for biological behavior at the individual cell level, but also for...

    Authors: Helena Soares, H. Susana Marinho, Carla Real and Fernando Antunes
    Citation: Genes & Nutrition 2013 9:371
  13. Folic acid is the key one-carbon donor required for de novo nucleotide and methionine synthesis. Its deficiency is associated with megaloblastic anemia, cancer and various complications of pregnancy. However, ...

    Authors: Shilpa Thakur, Som Dev Thakur, Nissar Ahmad Wani and Jyotdeep Kaur
    Citation: Genes & Nutrition 2013 9:369
  14. Dietary fat and vitamin A provide important precursors for potent bioactive ligands of nuclear hormone receptors, which regulate various enzymes involved in lipid homeostasis, metabolism and inflammation. We ...

    Authors: Kathrin Weiss, Johanna Mihály, Gerhard Liebisch, Tamás Marosvölgyi, Ada L. Garcia, Gerd Schmitz, Tamás Decsi and Ralph Rühl
    Citation: Genes & Nutrition 2013 9:368
  15. Although cell culture studies have provided landmark discoveries in the basic and applied life sciences, it is often under-appreciated that cells grown in culture are prone to generating artifacts. Here, we in...

    Authors: Sebastian Schaffer, Vanessa Y. M. Lam, Insa M. A. Ernst, Patricia Huebbe, Gerald Rimbach and Barry Halliwell
    Citation: Genes & Nutrition 2013 9:364
  16. Phytosterols have been widely studied for their cholesterol-lowering effect. Conjugated phytosterol forms have been found more active than free moieties. There are no reports about the sterol profile of black ...

    Authors: Rocio A. Chávez-Santoscoy, Armando R. Tovar, Sergio O. Serna-Saldivar, Nimbe Torres and Janet A. Gutiérrez-Uribe
    Citation: Genes & Nutrition 2013 9:367
  17. Accumulation of hepatic lipid droplet (HLD) is the hallmark pathology of non-alcoholic fatty liver disease (NAFLD). This study examined the effects of soy isoflavones (ISF) and different amounts of soy protein...

    Authors: Chao Wu Xiao, Carla M. Wood, Dorcas Weber, Syed A. Aziz, Rekha Mehta, Philip Griffin and Kevin A. Cockell
    Citation: Genes & Nutrition 2013 9:373
  18. Induction of brown-like adipocytes (brite) in white adipose tissues may allow the conversion of lipid storage cells in fat-burning cells. Little is known concerning browning potential in males compared with f...

    Authors: María Servera, Nora López, Francisca Serra and Andreu Palou
    Citation: Genes & Nutrition 2013 9:372
  19. Fish oil supplementation provides an inconsistent degree of protection from cardiovascular disease (CVD), which may be attributed to genetic variation. Single nucleotide polymorphisms (SNPs) in the elongation-...

    Authors: Aseel AlSaleh, Zoitsa Maniou, Fiona J. Lewis, Wendy L. Hall, Thomas A. B. Sanders and Sandra D. O’Dell
    Citation: Genes & Nutrition 2013 9:362
  20. Nutrigenomics and nutrigenetics (hereafter NGx) have stimulated expectations for beneficial applications in public health and individuals. Yet, the potential achievability of such promise is not without socioe...

    Authors: T. Hurlimann, V. Menuz, J. Graham, J. Robitaille, M.-C. Vohl and B. Godard
    Citation: Genes & Nutrition 2013 9:370
  21. Cancer is a leading cause of death worldwide with colorectal cancer (CRC) ranking as the third contributing to overall cancer mortality. Non-digestible compounds such as dietary fiber have been inversely assoc...

    Authors: R. K. Cruz-Bravo, R. G. Guevara-González, M. Ramos-Gómez, B. D. Oomah, P. Wiersma, R. Campos-Vega and G. Loarca-Piña
    Citation: Genes & Nutrition 2013 9:359
  22. Genetic and nutritional factors play a role in determining the functionality of the one-carbon (1C) metabolism cycle, a network of biochemical reactions critical to intracellular processes. Genes encoding enzy...

    Authors: Vikki Ho, Thomas E. Massey and Will D. King
    Citation: Genes & Nutrition 2013 8:358
  23. Long-term fructose consumption has been shown to evoke leptin resistance, to elevate triglyceride levels and to induce insulin resistance and hepatic steatosis. Autophagy has been suggested to function in pro...

    Authors: Meiju Äijälä, Elina Malo, Olavi Ukkola, Risto Bloigu, Petri Lehenkari, Helena Autio-Harmainen, Merja Santaniemi and Y. Antero Kesäniemi
    Citation: Genes & Nutrition 2013 8:357
  24. Vitamin D receptor polymorphisms may predispose that not all individuals could have benefits from the nutritional supplementation of 25-hydroxyvitamin D. Furthermore, vitamin D-related cardiovascular effects m...

    Authors: Jose C. E. Serrano, David De Lorenzo, Anna Cassanye, Meritxell Martín-Gari, Alberto Espinel, Marco Antonio Delgado, Reinald Pamplona and Manuel Portero-Otin
    Citation: Genes & Nutrition 2013 8:356
  25. Malnutrition inflammation syndrome (MIS) is common among ESRD patients. In the present study, we have investigated the association of genetic markers associated with appetite and energy regulation with malnutr...

    Authors: Richa Sharma, Suraksha Agrawal, Anita Saxena, Manmohan Pandey and R. K. Sharma
    Citation: Genes & Nutrition 2013 8:353
  26. The PCMT1 gene encodes the protein repair enzyme protein-l-isoaspartate (d-aspartate) O-methyltransferase, which is known to protect certain neural cells against Bax-induced apoptosis. Previous studies have produ...

    Authors: Fang Wang, Jianhua Wang, Jin Guo, Xiaoli Chen, Zhen Guan, Huizhi Zhao, Hua Xie, Chi Liu, Yihua Bao, Jizhen Zou, Bo Niu and Ting Zhang
    Citation: Genes & Nutrition 2013 8:355
  27. There is a clear link between overweight, gain of white adipose tissue, and diabetes type 2 (T2D). The molecular mechanism of the gain of adipose tissue is linked with the expression of high mobility group pro...

    Authors: Dominique Nadine Markowski, Helge Wilhelm Thies, Andrea Gottlieb, Heiner Wenk, Manfred Wischnewsky and Jörn Bullerdiek
    Citation: Genes & Nutrition 2013 8:354
  28. Gene–environment interactions need to be studied to better understand the obesity. We aimed at determining whether genetic susceptibility to obesity associates with diet intake levels and whether diet intakes ...

    Authors: Gull Rukh, Emily Sonestedt, Olle Melander, Bo Hedblad, Elisabet Wirfält, Ulrika Ericson and Marju Orho-Melander
    Citation: Genes & Nutrition 2013 8:352
  29. As a result of expanding scientific understanding of the interplay between genetics and dietary risk factors, those involved in nutritional management need to understand genetics and nutritional genomics in or...

    Authors: Jorja Collins, Brenda Bertrand, Veronica Hayes, Sherly X. Li, Jane Thomas, Helen Truby and Kevin Whelan
    Citation: Genes & Nutrition 2013 8:351
  30. The serotonergic pathway plays a major role in the development of obesity. Its activity can be modulated by the 5-HT transporter–linked polymorphic region in the SLC6A4 gene and the upstream variable number of...

    Authors: Dirk Wallmeier, Julia K. Winkler, Thomas Fleming, Annika Woehning, Katharina Huennemeyer, Eva Roeder, Peter P. Nawroth, Hans-Christoph Friederich, Christian Wolfrum, Jobst-Hendrik Schultz and Gottfried Rudofsky
    Citation: Genes & Nutrition 2013 8:350
  31. It is becoming increasingly apparent that responsiveness to dietary fat composition is heterogeneous and dependent on the genetic make-up of the individual. The aim of this study was to evidence a genotype-rel...

    Authors: Elisa Boschetti, Mattia Di Nunzio, Francesca Danesi, Vitaliano Tugnoli and Alessandra Bordoni
    Citation: Genes & Nutrition 2013 8:349
  32. Vitamin C is known to protect mucosal tissues from oxidative stress and inhibit nitrosamine formation in the stomach. High consumption of fruits, particularly citrus, and higher circulating vitamin C concentra...

    Authors: Eric J. Duell, Leila Lujan-Barroso, Claudia Llivina, Xavier Muñoz, Mazda Jenab, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Antoine Racine, Heiner Boeing, Brian Buijsse, Federico Canzian, Theron Johnson, Christine Dalgård, Kim Overvad, Anne Tjønneland, Anja Olsen…
    Citation: Genes & Nutrition 2013 8:346
  33. The anti-inflammatory potential of eight indigenous probiotic Lactobacillus isolates was evaluated in vitro in terms of modulating the expression of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) in...

    Authors: V. Aparna Sudhakaran, Harsh Panwar, Ritu Chauhan, Raj Kumar Duary, Rahul Kumar Rathore, Virender Kumar Batish and Sunita Grover
    Citation: Genes & Nutrition 2013 8:347
  34. We aimed to explore whether vegetable consumption according to guidelines has beneficial health effects determined with classical biomarkers and nutrigenomics technologies. Fifteen lean (age 36 ± 7 years; BMI ...

    Authors: W. J. Pasman, M. J. van Erk, W. A. A. Klöpping, L. Pellis, S. Wopereis, S. Bijlsma, H. F. J. Hendriks and A. F. M. Kardinaal
    Citation: Genes & Nutrition 2013 8:343
  35. Mice fed long-term high-fat diets (HFD) are an established model for human metabolic disorders, such as obesity and diabetes. However, also the effects of short-term HFD feeding should be investigated to under...

    Authors: Michela Lizier, Lorenzo Bomba, Andrea Minuti, Fatima Chegdani, Jessica Capraro, Barbara Tondelli, Raffaele Mazza, Maria Luisa Callegari, Erminio Trevisi, Filippo Rossi, Paolo Ajmone Marsan and Franco Lucchini
    Citation: Genes & Nutrition 2013 8:344
  36. n-3 Polyunsaturated fatty acids (n-3 PUFAs) have anti-obesity effects that may modulate risk of obesity, in part, through interactions with genetic factors. Genome-wide association studies (GWAS) have identifi...

    Authors: Dominick J. Lemas, Yann C. Klimentidis, Howard H. Wiener, Diane M. O’Brien, Scarlett E. Hopkins, David B. Allison, Jose R. Fernandez, Hemant K. Tiwari and Bert B. Boyer
    Citation: Genes & Nutrition 2013 8:340
  37. This special section of Genes and Nutrition presents a baseline analysis of ethical and legal issues undertaken within the EU FP7 research project Food4Me, which investigates the feasibility today of the visio...

    Authors: U. Görman
    Citation: Genes & Nutrition 2013 8:341
  38. Personalized nutrition has the potential to enhance individual health control. It could be seen as a means to strengthen people’s autonomy as they learn more about their personal health risks, and receive diet...

    Authors: Karin Nordström, Niklas Juth, Sofia Kjellström, Franck L. B. Meijboom and Ulf Görman
    Citation: Genes & Nutrition 2013 8:337
  39. In personalized nutrition, food is a tool for good health, implying an instrumental relationship between food and health. Food receives a secondary value, while health would appear to be a descriptive biologic...

    Authors: Karin Nordström, Christian Coff, Håkan Jönsson, Lennart Nordenfelt and Ulf Görman
    Citation: Genes & Nutrition 2013 8:336
  40. Childhood obesity is a worldwide health concern with a multifaceted and sometimes confounding etiology. Dairy products have been implicated as both pro- and anti-obesogenic, perhaps due to the confounding rela...

    Authors: Adil J. Malek, Yann C. Klimentidis, Kenneth P. Kell and José R. Fernández
    Citation: Genes & Nutrition 2013 8:335
  41. Healthier eating is a global challenge for chronic disease control. Food and Health Research in Europe (FAHRE) surveyed research structures and programmes in 32 countries, and reviewed research needs and gaps ...

    Authors: Mark McCarthy
    Citation: Genes & Nutrition 2013 8:334
  42. Consumers often have a positive attitude to the option of receiving personalized nutrition advice based upon genetic testing, since the prospect of enhancing or maintaining one’s health can be perceived as emp...

    Authors: Jennie Ahlgren, Anders Nordgren, Maud Perrudin, Amber Ronteltap, Jean Savigny, Hans van Trijp, Karin Nordström and Ulf Görman
    Citation: Genes & Nutrition 2013 8:331
  43. A long-term high-fat diet may result in a fatty liver. However, whether or not high-fat diets affect the hepatic circadian clock is controversial. The objective of this study is to investigate the effects of t...

    Authors: Xiaoyan Wang, Jie Xue, Juan Yang and Meilin Xie
    Citation: Genes & Nutrition 2013 8:333
  44. Diet is generally believed to affect the aging process. The effects of complex foods on life span can be investigated using simple models that produce rapid results and allow the identification of food–gene in...

    Authors: Stefanie Grünwald, Julia Stellzig, Iris V. Adam, Kristine Weber, Sarai Binger, Michael Boll, Eileen Knorr, Richard M. Twyman, Andreas Vilcinskas and Uwe Wenzel
    Citation: Genes & Nutrition 2013 8:330
  45. The detrimental effects of high oxygen supplementation have been widely reported. Conversely, few is known about the effects of exposure to mild hyperoxic conditions, an interesting issue since the use of oxyg...

    Authors: Francesco Cimino, Antonio Speciale, Sirajudheen Anwar, Raffaella Canali, Elisabetta Ricciardi, Fabio Virgili, Domenico Trombetta and Antonina Saija
    Citation: Genes & Nutrition 2012 8:324

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