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  1. Vitamin D deficiency is a well-documented public health issue with both genetic and environmental determinants. Populations living at far northern latitudes are vulnerable to vitamin D deficiency and its healt...

    Authors: Stella Aslibekyan, Laura K. Vaughan, Howard W. Wiener, Bertha A. Hidalgo, Dominick J. Lemas, Diane M. O’Brien, Scarlett E. Hopkins, Kimber L. Stanhope, Peter J. Havel, Kenneth E. Thummel, Bert B. Boyer and Hemant K. Tiwari

    Citation: Genes & Nutrition 2016 11:23

    Content type: Research

    Published on:

  2. Our previous study showed that fatty acids extract obtained from CLA-enriched egg yolks (EFA-CLA) suppressed the viability of MCF-7 cancer cell line more effectively than extract from non-enriched egg yolks (E...

    Authors: Aneta A. Koronowicz, Paula Banks, Dominik Domagała, Adam Master, Teresa Leszczyńska, Ewelina Piasna, Mariola Marynowska and Piotr Laidler

    Citation: Genes & Nutrition 2016 11:22

    Content type: Research

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    The Erratum to this article has been published in Genes & Nutrition 2016 11:24

  3. VAAM is an amino acid mixture that simulates the composition of Vespa larval saliva. VAAM enhanced physical endurance of mice and have been used by athletes as a supplementary drink before exercise. However, ther...

    Authors: Fumika Shinozaki, Takashi Abe, Asuka Kamei, Yuki Watanabe, Akihito Yasuoka, Kosuke Shimada, Kaori Kondo, Soichi Arai, Kota Kumagai, Takashi Kondo and Keiko Abe

    Citation: Genes & Nutrition 2016 11:21

    Content type: Research

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  4. By taking diet quality into account, we may clarify the relationship between genetically elevated triglycerides (TG) and low-density lipoprotein-cholesterol (LDL-C), and better understand the inconsistent resu...

    Authors: Sophie Hellstrand, Ulrika Ericson, Christina-Alexandra Schulz, Isabel Drake, Bo Gullberg, Bo Hedblad, Gunnar Engström, Marju Orho-Melander and Emily Sonestedt

    Citation: Genes & Nutrition 2016 11:20

    Content type: Research

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  5. Mitochondria are of major importance in oocyte and early embryo, playing a key role in maintaining energy homeostasis. Epidemiological findings indicate that maternal undernutrition-induced mitochondrial dysfu...

    Authors: Tiande Zou, Bing Yu, Jie Yu, Xiangbing Mao, Ping Zheng, Jun He, Zhiqing Huang, Yue Liu and Daiwen Chen

    Citation: Genes & Nutrition 2016 11:19

    Content type: Research

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  6. Cumulating evidence underlines the role of adipose tissue metallothionein (MT) in the development of obesity and type 2 diabetes. Fasting/refeeding was shown to affect MT gene expression in the rodent liver. T...

    Authors: Sylwia Szrok, Ewa Stelmanska, Jacek Turyn, Aleksandra Bielicka-Gieldon, Tomasz Sledzinski and Julian Swierczynski

    Citation: Genes & Nutrition 2016 11:18

    Content type: Research

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  7. Marine long-chain polyunsaturated fatty acids are susceptible to oxidation, generating a range of different oxidation products with suggested negative health effects. The aim of the present study was to utiliz...

    Authors: Mari C. W. Myhrstad, Inger Ottestad, Clara-Cecilie Günther, Einar Ryeng, Marit Holden, Astrid Nilsson, Kirsti W. Brønner, Achim Kohler, Grethe I. A. Borge, Kirsten B. Holven and Stine M. Ulven

    Citation: Genes & Nutrition 2016 11:16

    Content type: Research Paper

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  8. Non-celiac wheat sensitivity is an emerging wheat-related syndrome showing peak prevalence in Western populations. Recent studies hypothesize that new gliadin alleles introduced in the human diet by replacemen...

    Authors: Marco Sazzini, Sara De Fanti, Anna Cherubini, Andrea Quagliariello, Giuseppe Profiti, Pier Luigi Martelli, Rita Casadio, Chiara Ricci, Massimo Campieri, Alberto Lanzini, Umberto Volta, Giacomo Caio, Claudio Franceschi, Enzo Spisni and Donata Luiselli

    Citation: Genes & Nutrition 2016 11:15

    Content type: Research

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  9. Environmental factors are well-known causes of diseases. However, aside from a handful of risk indicators, genes’ encoding susceptibility to chronic illnesses and their associated environmental triggers are la...

    Authors: Xin Zhou, MengMeng Xu, Liyang Wang, Yulian Mu, Rui Feng, Zhilong Dong, Yuexin Pan, Xunzhang Chen, Yongfeng Liu, Shangen Zheng, Donald D. Anthony, Jianjie Ma, Williams B. Isaacs and Xuehong Xu

    Citation: Genes & Nutrition 2016 11:14

    Content type: Research

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  10. Caloric restriction (CR) is considered to increase lifespan and to prevent various age-related diseases in different nonhuman organisms. Only a limited number of CR studies have been performed on humans, and r...

    Authors: I. P. G. Van Bussel, A. Jolink-Stoppelenburg, C. P. G. M. De Groot, M. R. Müller and L. A. Afman

    Citation: Genes & Nutrition 2016 11:13

    Content type: Research

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  11. Biomarkers of nutrient intake or nutrient status are important objective measures of foods/nutrients as one of the most important environmental factors people are exposed to. It is very difficult to obtain acc...

    Authors: T. Holen, F. Norheim, T. E. Gundersen, P. Mitry, J. Linseisen, P. O. Iversen and C. A. Drevon

    Citation: Genes & Nutrition 2016 11:12

    Content type: Review

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  12. MicroRNAs (miRNAs) are small non-coding RNAs involved in the modulation of gene expression and in the control of numerous cell functions. Alterations of miRNA patterns frequently occur in cancer and metabolic ...

    Authors: Giuseppe Iacomino, Paola Russo, Ilaria Stillitano, Fabio Lauria, Pasquale Marena, Wolfgang Ahrens, Pasquale De Luca and Alfonso Siani

    Citation: Genes & Nutrition 2016 11:7

    Content type: Research

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  13. TCF7L2 is a central transcription factor in the canonical wingless-type MMTV integration site (WNT) signaling pathway, and genetic variants in TCF7L2 have been found to interact with dietary fiber intake on type ...

    Authors: George Hindy, Inês G. Mollet, Gull Rukh, Ulrika Ericson and Marju Orho-Melander

    Citation: Genes & Nutrition 2016 11:6

    Content type: Research

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  14. Emerging evidence suggests beneficial effects of omega-3 fatty acids on diabetic complications. The present study compared the progressive effects of metformin and flax/fish oil on lipid metabolism, inflammato...

    Authors: Abhijit Ghadge, Abhay Harsulkar, Manjiri Karandikar, Vijaya Pandit and Aniket Kuvalekar

    Citation: Genes & Nutrition 2016 11:10

    Content type: Research Paper

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  15. The optimal ratio of omega-6 to omega-3 polyunsaturated fatty acids (PUFAs) is important for keeping the homeostasis of biological processes and metabolism, yet the underlying biological mechanism is poorly un...

    Authors: Agnieszka Szostak, Magdalena Ogłuszka, Marinus F. W. te Pas, Ewa Poławska, Paweł Urbański, Edyta Juszczuk-Kubiak, Tadeusz Blicharski, Chandra Shekhar Pareek, Jenelle R. Dunkelberger, Jarosław O. Horbańczuk and Mariusz Pierzchała

    Citation: Genes & Nutrition 2016 11:9

    Content type: Research Paper

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  16. Insulin resistance is associated with impaired cardiac function, but the underlying molecular abnormalities are largely unexplained. Bilberry anthocyanin (BAcn) may be protective, as it appears to potentiate i...

    Authors: Shamjeet Singh, Thomas Netticadan and D. Dan Ramdath

    Citation: Genes & Nutrition 2016 11:8

    Content type: Research Paper

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  17. Adult skeletal muscle myogenesis depends on the activation of satellite cells that have the potential to differentiate into new fibers. Gamma-oryzanol (GO), a commercially available nutriactive phytochemical, ...

    Authors: K. A. Szcześniak, A. Ciecierska, P. Ostaszewski and T. Sadkowski

    Citation: Genes & Nutrition 2016 11:5

    Content type: Research

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  18. Diet has a great impact on the risk of developing features of metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), and cardiovascular diseases (CVD). We evaluated whether a long-term healthy Nordic diet...

    Authors: Lena Leder, Marjukka Kolehmainen, Ingunn Narverud, Ingrid Dahlman, Mari C. W. Myhrstad, Vanessa D. de Mello, Jussi Paananen, Carsten Carlberg, Ursula Schwab, Karl-Heinz Herzig, Lieselotte Cloetens, Matilda Ulmius Storm, Janne Hukkanen, Markku J. Savolainen, Fredrik Rosqvist, Kjeld Hermansen…

    Citation: Genes & Nutrition 2016 11:3

    Content type: Research

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  19. Menopausal symptoms are associated with inflammation. Curcumin is a well-known anti-inflammatory bioactive compound from turmeric whereas tetrahydrocurcumin (THC) is a major metabolite of curcumin that may hav...

    Authors: Sunmin Park, La Ra Lee, Ji Hyun Seo and Suna Kang

    Citation: Genes & Nutrition 2016 11:2

    Content type: Research

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  20. Considering that vitamin A deficiency modulates hepcidin expression and consequently affects iron metabolism, we evaluated the effect of vitamin A deficiency in the expression of genes involved in the hemojuve...

    Authors: Juliana Frossard Ribeiro Mendes, Egle Machado de Almeida Siqueira, João Gabriel Marques de Brito e Silva and Sandra Fernandes Arruda

    Citation: Genes & Nutrition 2016 11:1

    Content type: Research

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  21. Worldwide population is aging, and a large part of the growing burden associated with age-related conditions can be prevented or delayed by promoting healthy lifestyle and normalizing metabolic risk factors. H...

    Authors: Sébastien Lacroix, Mario Lauria, Marie-Pier Scott-Boyer, Luca Marchetti, Corrado Priami and Laura Caberlotto

    Citation: Genes & Nutrition 2015 10:58

    Content type: Research Paper

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  22. Induction of skeletal muscle (SM) mitochondrial stress by expression of uncoupling protein 1 (UCP1) in mice results in a healthy metabolic phenotype associated with increased secretion of FGF21 from SM. Here,...

    Authors: Anja Voigt, Yvonne Katterle, Melanie Kahle, Reinhart Kluge, Annette Schürmann, Hans-Georg Joost and Susanne Klaus

    Citation: Genes & Nutrition 2015 10:57

    Content type: Research Paper

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  23. The extracellular matrix (ECM) of adipocytes is important for body weight regulation. Here, we investigated whether genetic variation in ECM-related genes is associated with weight regain among participants of...

    Authors: Nadia J. T. Roumans, Roel G. Vink, Marij Gielen, Maurice P. Zeegers, Claus Holst, Ping Wang, Arne Astrup, Wim H. Saris, Armand Valsesia, Jörg Hager, Marleen A. van Baak and Edwin C. M. Mariman

    Citation: Genes & Nutrition 2015 10:56

    Content type: Research Paper

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  24. An iron-deficient rat model was established and used to determine the effects of different iron sources on iron metabolism and absorption. Iron-deficient rats were assigned to one of three treatment groups, an...

    Authors: Yuzhe Zhang, Xiaoming Sun, Chunyan Xie, Xugang Shu, Abimbola Oladele Oso, Zheng Ruan, Ze-yuan Deng, Xin Wu and Yulong Yin

    Citation: Genes & Nutrition 2015 10:54

    Content type: Research Paper

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  25. Polyunsaturated fatty acids (PUFAs) have a major impact on human health. Recent genome-wide association studies (GWAS) have identified several genetic loci that are associated with plasma levels of n-3 and n-6...

    Authors: Rajkumar Dorajoo, Ye Sun, Yi Han, Tingjing Ke, Ayala Burger, Xuling Chang, Hui Qi Low, Weihua Guan, Rozenn N. Lemaitre, Chiea-Chuen Khor, Jian-Min Yuan, Woon-Puay Koh, Choon Nam Ong, E. Shyong Tai, Jianjun Liu, Rob M. van Dam…

    Citation: Genes & Nutrition 2015 10:53

    Content type: Research Paper

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  26. This clinical trial aimed to discover the effects of probiotic soy milk and soy milk on MLH1 and MSH2 promoter methylation, and oxidative stress among type II diabetic patients. Forty patients with type II dia...

    Authors: Mitra Hariri, Rasoul Salehi, Awat Feizi, Maryam Mirlohi, Reza Ghiasvand and Nahal Habibi

    Citation: Genes & Nutrition 2015 10:52

    Content type: Research Paper

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  27. Epigenetic and posttranslational modifications of the expression of cell cycle-relevant genes or proteins like p21, e.g., by miRNAs are crucial mechanisms in the development or prevention of colon cancer. The pr...

    Authors: W. Schlörmann, S. Naumann, C. Renner and M. Glei

    Citation: Genes & Nutrition 2015 10:50

    Content type: Research Paper

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  28. Colorectal cancer (CRC) is a disease whose genesis may include metabolic dysregulation. Cancer stem cells are attractive targets for therapeutic interventions since their aberrant expansion may underlie tumor ...

    Authors: Maria Theresa E. Montales, Rosalia C. M. Simmen, Ederlan S. Ferreira, Valdir A. Neves and Frank A. Simmen

    Citation: Genes & Nutrition 2015 10:49

    Content type: Research Paper

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  29. The hypothalamus integrates energy balance information from the periphery using different neuronal subtypes within each of the hypothalamic areas. However, the effects of prandial state on global mRNA, microRN...

    Authors: Hao Jiang, Thero Modise, Richard Helm, Roderick V. Jensen and Deborah J. Good

    Citation: Genes & Nutrition 2015 10:48

    Content type: Research Paper

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  30. The inhibitory neurotransmitter GABA (γ-aminobutyric acid) is synthesized by glutamic acid decarboxylase, which is expressed in the central nervous system and in various other tissues including the intestine. ...

    Authors: Hannah-Sophie Braun, Gerhard Sponder, Robert Pieper, Jörg R. Aschenbach and Carolin Deiner

    Citation: Genes & Nutrition 2015 10:47

    Content type: Research Paper

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  31. Obesity is associated with chronic diseases such as fatty liver, type 2 diabetes, cardiovascular disease, and severe metabolic syndrome. Obesity causes metabolic impairment including excessive lipid accumulat...

    Authors: Ji-Young Ann, Hyeyoon Eo and Yunsook Lim

    Citation: Genes & Nutrition 2015 10:46

    Content type: Research Paper

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  32. The usefulness of zinc transporter and metallothionein (MT) gene expressions to detect changes in zinc intake remains unclear. This pilot study aimed to determine the effects of zinc supplementation on zinc tr...

    Authors: Anna Chu, Meika Foster, Sarah Ward, Kamrul Zaman, Dale Hancock, Peter Petocz and Samir Samman

    Citation: Genes & Nutrition 2015 10:44

    Content type: Research Paper

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  33. Human and animal studies suggest an interaction between the Pro12Ala polymorphism of PPARG and dietary fat. In this randomized crossover clinical trial, we investigated whether subjects with the Pro12Pro and Ala...

    Authors: Jussi Pihlajamäki, Ursula Schwab, Dorota Kaminska, Jyrki Ågren, Johanna Kuusisto, Marjukka Kolehmainen, Jussi Paananen, Markku Laakso and Matti Uusitupa

    Citation: Genes & Nutrition 2015 10:43

    Content type: Research Paper

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  34. Through a Privacy Calculus (i.e. risk–benefit trade-off) lens, this study identifies factors that contribute to consumers’ adoption of personalised nutrition services. We argue that consumers’ intention to ado...

    Authors: Aleksandra Berezowska, Arnout R. H. Fischer, Amber Ronteltap, Ivo A. van der Lans and Hans C. M. van Trijp

    Citation: Genes & Nutrition 2015 10:42

    Content type: Research Paper

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  35. 18β-Glycyrrhetinic acid (18β-GA) has been proposed as a promising hepatoprotective agent. The current study aimed to investigate the protective action and the possible mechanisms of 18β-GA against cyclophospha...

    Authors: Ayman M. Mahmoud and Hussein S. Al Dera

    Citation: Genes & Nutrition 2015 10:41

    Content type: Research Paper

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    The Erratum to this article has been published in Genes & Nutrition 2016 11:31

  36. We investigated the effect of short-term fasting on coordinate changes in the fatty acid composition of adipose triacylglycerol (TAG), serum non-esterified fatty acids (NEFA), liver TAG, and serum TAG and phos...

    Authors: Kristin A. Marks, Phillip M. Marvyn, Juan J. Aristizabal Henao, Ryan M. Bradley, Ken D. Stark and Robin E. Duncan

    Citation: Genes & Nutrition 2015 10:39

    Content type: Research Paper

    Published on:

    The Erratum to this article has been published in Genes & Nutrition 2015 10:45

  37. Two cases of zinc deficiency in breastfed neonates were investigated where zinc levels in the mothers’ milk were reduced by more than 75 % compared to normal. The objective of this study was to find the molec...

    Authors: Loveleen Kumar, Agnes Michalczyk, Jill McKay, Dianne Ford, Taiho Kambe, Lee Hudek, George Varigios, Philip E. Taylor and M. Leigh Ackland

    Citation: Genes & Nutrition 2015 10:38

    Content type: Research Paper

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  38. Angiotensinogen (AGT), its active fragments and microRNA-31 (miR-31) play an important role in adipocyte differentiation. AGT contains a miR-31 polymorphic binding site. We hypothesize that the rs7079 polymorp...

    Authors: Jan Machal, Jan Novak, Renata Hezova, Filip Zlamal, Anna Vasku, Ondrej Slaby and Julie Bienertova-Vasku

    Citation: Genes & Nutrition 2015 10:37

    Content type: Research Paper

    Published on:

  39. Nutritional systems biology is an evolving research field aimed at understanding nutritional processes at a systems level. It is known that the development of cancer can be influenced by the nutritional status...

    Authors: Martina Kutmon, Susan L. Coort, Kim de Nooijer, Claire Lemmens and Chris T. Evelo

    Citation: Genes & Nutrition 2015 10:35

    Content type: Research Paper

    Published on:

  40. The aim of the study was to assess the relationship between sweet taste genes and dental caries prevalence in a large sample of adults. In addition, the association between sweet liking and sugar intake with ...

    Authors: Antonietta Robino, Lorenzo Bevilacqua, Nicola Pirastu, Roberta Situlin, Roberto Di Lenarda, Paolo Gasparini and Chiara Ottavia Navarra

    Citation: Genes & Nutrition 2015 10:34

    Content type: Research Paper

    Published on:

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