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  1. The nuclear factor (NF)-κB is a primary regulator of inflammatory responses and may be linked to pathology associated with obesity. We investigated the progression of NF-κB activity during a 12-week feeding pe...

    Authors: Harald Carlsen, Fred Haugen, Susanne Zadelaar, Robert Kleemann, Teake Kooistra, Christian A. Drevon and Rune Blomhoff
    Citation: Genes & Nutrition 2009 4:133
  2. All definitions of the terms ‘oxidative stress’ and ‘antioxidants’ implicate that oxidants are just damaging. However, there is increasing evidence that reactive oxygen species (ROS) are not only toxic but tha...

    Authors: Regina Brigelius-Flohé
    Citation: Genes & Nutrition 2009 4:131
  3. The aim of this study was to investigate the possible associations between insertion/deletion (ID) polymorphism in angiotensin-converting enzyme (ACE) (dbSNP rs 4646994) with the food intake and body compositi...

    Authors: Julie Bienertova-Vasku, Petr Bienert, Lenka Sablikova, Lenka Slovackova, Martin Forejt, Zlata Piskackova, Lenka Kucerova, Katerina Heczkova, Zuzana Brazdova and Anna Vasku
    Citation: Genes & Nutrition 2009 4:130
  4. Omega-3 fatty acids (FAs) are natural ligands of the peroxisome proliferator-activated receptor-α (PPARα), a nuclear receptor that modulates expression levels of genes involved in lipid metabolism. The L162V p...

    Authors: Iwona Rudkowska, Christophe Garenc, Patrick Couture and Marie-Claude Vohl
    Citation: Genes & Nutrition 2009 4:129
  5. Recent epidemiological data suggest that β-carotene may be protective against metabolic diseases in which adipose tissue plays a key role. Adipose tissue constitutes the major β-carotene storage tissue and its...

    Authors: Franck Tourniaire, Erwan Gouranton, Johannes von Lintig, Jaap Keijer, M. Luisa Bonet, Jaume Amengual, Georg Lietz and Jean-François Landrier
    Citation: Genes & Nutrition 2009 4:128
  6. Progenitor cells have been extensively studied and therapeutically applied in tissue reconstructive therapy. Stromal vascular fraction (SVF) cells, which are derived from adipose tissue, may represent a potent...

    Authors: Agnieszka Sliwa, A. Balwierz, B. Kiec-Wilk, A. Polus, A. Knapp and A. Dembinska-Kiec
    Citation: Genes & Nutrition 2009 4:127
  7. Folate is a B vitamin required for one-carbon transfer reactions including methylation of cell macromolecules including DNA and synthesis of the purines adenosine and guanosine and the pyrimidine thymidine. Ep...

    Authors: John C. Mathers
    Citation: Genes & Nutrition 2009 4:126
  8. Foetal growth is particularly sensitive to the protein content of the mother’s diet. Microarray data from the foetal liver of pregnant rats fed normal (HP) or reduced protein diets (LP) were compared by gene s...

    Authors: Christopher J. McNeil, Susan M. Hay, Garry J. Rucklidge, Martin D. Reid, Gary J. Duncan and William David Rees
    Citation: Genes & Nutrition 2009 4:125
  9. Alternatives to animal testing and the identification of reliable methods that may decrease the need for animals are currently the subject of intense investigation worldwide. Alternative testing procedures are...

    Authors: M. Penza, M. Jeremic, C. Montani, M. Unkila, L. Caimi, G. Mazzoleni and Diego Di Lorenzo
    Citation: Genes & Nutrition 2009 4:124
  10. New ‘omics’ technologies are changing nutritional sciences research. They enable to tackle increasingly complex questions but also increase the need for collaboration between research groups. An important chal...

    Authors: Ulrich Harttig, Anthony J. Travis, Philippe Rocca-Serra, Marten Renkema, Ben van Ommen and Heiner Boeing
    Citation: Genes & Nutrition 2009 4:123
  11. Combination of decreased energy expenditure and increased food intake results in fat accumulation either in the abdominal site (upper body obesity, UBO) or on the hips (lower body obesity, LBO). In this study,...

    Authors: Marijana Radonjic, Marjan J. van Erk, Wilrike J. Pasman, Heleen M. Wortelboer, Henk F. J. Hendriks and Ben van Ommen
    Citation: Genes & Nutrition 2009 4:122
  12. Blood cells and biofluid proteomics are emerging as a valuable tool to assess effects of interventions on health and disease. This study is aimed to assess the amount and variability of proteins from platelets...

    Authors: L. Katie Crosley, Susan J. Duthie, Abigael C. Polley, Freek G. Bouwman, Carolin Heim, Francis Mulholland, Graham Horgan, Ian T. Johnson, Edwin C. Mariman, Ruan M. Elliott, Hannelore Daniel and Baukje de Roos
    Citation: Genes & Nutrition 2009 4:121
  13. Zinc (Zn) is required for numerous metabolic processes serving both a structural and catalytic role. The mammary gland has a unique Zn requirement resulting from the need to also transfer an extraordinary amou...

    Authors: Shannon L. Kelleher, Young Ah Seo and Veronica Lopez
    Citation: Genes & Nutrition 2009 4:119
  14. We conducted an in-depth investigation of the effects of conjugated linoleic acid (CLA) on the expression of key metabolic genes and genes of known importance in intestinal lipid metabolism using the Caco-2 ce...

    Authors: Eileen F. Murphy, Guido J. Hooiveld, Michael Müller, Raffaelle A. Calogero and Kevin D. Cashman
    Citation: Genes & Nutrition 2009 4:116
  15. Omics technology used for large-scale measurements of gene expression is rapidly evolving. This work pointed out the need of an extensive bioinformatics analyses for array quality assessment before and after g...

    Authors: Rachel I. M. van Haaften, Cristina Luceri, Arie van Erk and Chris T. A. Evelo
    Citation: Genes & Nutrition 2009 4:115
  16. Previous studies have illustrated the importance of leptin receptor (OB-Rb) mediated action on adipocytes in the regulation of body weight. The aim of the present study was to investigate in male and female ra...

    Authors: T. Priego, J. Sánchez, A. Palou and C. Picó
    Citation: Genes & Nutrition 2009 4:114
  17. Obesity is characterized by an excess storage of body fat and promotes the risk for complex disease traits such as diabetes mellitus and cardiovascular diseases. The obesity prevalence in Europe is rising and ...

    Authors: Florian Bolze and M. Klingenspor
    Citation: Genes & Nutrition 2009 4:117
  18. Reactive oxygen species (ROS) are thought to be a driving force in the aging process. In transgenic Caenorhabditis elegans expressing green fluorescent protein (GFP) under control of the hsp-16.2 promoter (CL2070...

    Authors: Kai Hartwig, Tanja Heidler, Jan Moch, Hannelore Daniel and Uwe Wenzel
    Citation: Genes & Nutrition 2009 4:113
  19. The vgf gene regulates energy homeostasis and the VGF-derived peptide TLQP-21 centrally exerts catabolic effects in mice and hamsters. Here, we investigate the effect of chronic intracerebroventricular (icv) inje...

    Authors: Alessandro Bartolomucci, Elena Bresciani, Ilaria Bulgarelli, Antonello E. Rigamonti, Tiziana Pascucci, Andrea Levi, Roberta Possenti, Antonio Torsello, Vittorio Locatelli, Eugenio E. Muller and Anna Moles
    Citation: Genes & Nutrition 2009 4:110
  20. Epidemiological studies suggest that high fish intake is associated with a decreased risk of colorectal cancer which has been linked to the high content of the n-3 polyunsaturated fatty acids (PUFAs) eicosapentae...

    Authors: Nina Habermann, Elizabeth K. Lund, Beatrice L. Pool-Zobel and Michael Glei
    Citation: Genes & Nutrition 2009 4:112
  21. To investigate the effect of RXRα deficiency in liver on angiogenesis, hepatocyte RXRα-deficient and control wild-type mice were fed either standard or high-fat diet (HF) for 7 weeks. In the 6th week of feedin...

    Authors: Urszula Razny, Lukasz Wator, Anna Polus, Yu-Jui Yvonne Wan, Grzegorz Dyduch, Romana Tomaszewska and Aldona Dembinska-Kiec
    Citation: Genes & Nutrition 2009 4:111
  22. The mycotoxin ochratoxin A (OTA), which is produced by Aspergillus and Penicillium subspecies, is a frequently present contaminant of food and feedstuffs. OTA exhibits a wide range of toxic activities including n...

    Authors: Xiangnan Zhang, Christine Boesch-Saadatmandi, Yijia Lou, Siegfried Wolffram, Patricia Huebbe and Gerald Rimbach
    Citation: Genes & Nutrition 2009 4:109
  23. Male C57BL/6 mice were fed diets supplemented with either β-carotene (BC) or lycopene (LY) that were formulated for human consumption. Four weeks of dietary supplementations results in plasma and lung caroteno...

    Authors: Hnin H. Aung, Vihas T. Vasu, Giuseppe Valacchi, Ana M. Corbacho, Rama S. Kota, Yunsook Lim, Ute C. Obermueller-Jevic, Lester Packer, Carroll E. Cross and Kishorchandra Gohil
    Citation: Genes & Nutrition 2008 4:108
  24. Time course experiments are aimed at characterizing the dynamic regulation of gene expression in biological systems. Data are collected at different time points to monitor the dynamic behaviour of gene express...

    Authors: M. Baccini, G. Tonini and A. Biggeri
    Citation: Genes & Nutrition 2008 3:105
  25. Leptin is prompt to drive angiogenesis, effecting proper vascularisation. Tissue remodeling (including adipose organ) is associated with the angiogenic response. The aim of this study was to investigate the ef...

    Authors: Lukasz Wator, Urszula Razny, Adriana Balwierz, Anna Polus, Hans G. Joost, Grzegorz Dyduch, Romana Tomaszewska and Aldona Dembinska-Kiec
    Citation: Genes & Nutrition 2008 3:103
  26. Authors: Michela Baccini, Eva-Maria Bachmaier, Annibale Biggeri, Mark V. Boekschoten, Freek G. Bouwman, Lorraine Brennan, Robert Caesar, Saverio Cinti, Susan L. Coort, Katie Crosley, Hannelore Daniel, Christian A. Drevon, Susan Duthie, Lars Eijssen, Ruan M. Elliott, Marjan van Erk…
    Citation: Genes & Nutrition 2008 3:102
  27. Insulin resistance is a characteristic of type-2 diabetes and its development is associated with an increased fat consumption. Muscle is one of the tissues that becomes insulin resistant after high fat (HF) fe...

    Authors: Susan L. M. Coort, Martijn P. van Iersel, Marjan van Erk, Teake Kooistra, Robert Kleemann and Chris T. A. Evelo
    Citation: Genes & Nutrition 2008 3:100
  28. Diagrams and models of biological pathways are useful tools in biology. Pathway diagrams are mainly used for illustrative purposes for instance in textbooks and in presentations. Pathway models are used in the...

    Authors: A. S. Waagmeester, T. Kelder and C. T. A. Evelo
    Citation: Genes & Nutrition 2008 3:98
  29. Metabolic syndrome (MS) is a cluster of metabolic abnormalities associated with an increased risk of developing cardio-vascular diseases, stroke or type II diabetes. Overall, the aetiology of MS is complex and...

    Authors: Fabien Szabo de Edelenyi, Louisa Goumidi, Sandrine Bertrais, Catherine Phillips, Ross MacManus, Helen Roche, Richard Planells and Denis Lairon
    Citation: Genes & Nutrition 2008 3:97
  30. The goal of this study was to investigate the effect of a short-term nutritional intervention on gene expression in adipose tissue from lean and overweight subjects. Gene expression profiles were measured afte...

    Authors: Marjan J. van Erk, Wilrike J. Pasman, Heleen M. Wortelboer, Ben van Ommen and Henk F. J. Hendriks
    Citation: Genes & Nutrition 2008 3:96
  31. NuGO, the European Nutrigenomics Organization, utilizes 31 powerful computers for, e.g., data storage and analysis. These so-called black boxes (NBXses) are located at the sites of different partners. NuGO dec...

    Authors: P. J. De Groot, C. Reiff, C. Mayer and M. Müller
    Citation: Genes & Nutrition 2008 3:93
  32. Flavonoids exert a multiplicity of neuroprotective actions within the brain, including a potential to protect neurons against injury induced by neurotoxins, an ability to suppress neuroinflammation, and the po...

    Authors: David Vauzour, Katerina Vafeiadou, Ana Rodriguez-Mateos, Catarina Rendeiro and Jeremy P. E. Spencer
    Citation: Genes & Nutrition 2008 3:91
  33. Human nutrition and metabolism may serve as the paradigm for the complex interplay of the genome with its environment. The concept of nutrigenomics now enables science with new tools and comprehensive analytic...

    Authors: Hannelore Daniel, Christian A. Drevon, Ulla I. Klein, Robert Kleemann and Ben van Ommen
    Citation: Genes & Nutrition 2008 3:89
  34. Nutritional systems biology may be defined as the ultimate goal of molecular nutrition research, where all relevant aspects of regulation of metabolism in health and disease states at all levels of its complex...

    Authors: Ben van Ommen, Duccio Cavallieri, Helen M. Roche, Ulla I. Klein and Hannelore Daniel
    Citation: Genes & Nutrition 2008 3:90
  35. The aetiology of breast cancer is complex and multifactorial, and may include diet and xenobiotic compounds. A change in diet affects nutrient levels in blood, but to what extent diet can affect micronutrient ...

    Authors: Ferdinando Mannello, Gaetana A. Tonti and Franco Canestrari
    Citation: Genes & Nutrition 2008 3:87
  36. Nutrition science finds itself at a major crossroad. On the one hand we can continue the current path, which has resulted in some substantial advances, but also many conflicting messages which impair the trust...

    Authors: Christine M. Williams, Jose M. Ordovas, Dennis Lairon, John Hesketh, Georg Lietz, Mike Gibney and Ben van Ommen
    Citation: Genes & Nutrition 2008 3:86
  37. In quantifying the beneficial effect of dietary interventions in healthy subjects, nutrition research meets a number of new challenges. Inter individual variation in biomarker values often is larger than the e...

    Authors: Ben van Ommen, Jaap Keijer, Robert Kleemann, Ruan Elliott, Christian A. Drevon, Harry McArdle, Mike Gibney and Michael Müller
    Citation: Genes & Nutrition 2008 3:84
  38. Low plasma levels of high-density lipoprotein cholesterol (HDL-C) are identified as a risk factor for cardiovascular disease (CVD). Sexual dimorphism, however, is widely reported in both HDL-C and CVD, with th...

    Authors: M. J. Mosher, L. A. Lange, B. V. Howard, E. T. Lee, L. G. Best, R. R. Fabsitz, J. W. MacCluer and K. E. North
    Citation: Genes & Nutrition 2008 3:75
  39. Colorectal cancer and myocardial infarction are associated at population level and in autoptic studies. Furthermore, they share many blood variables: cholesterol, triglycerides and HDL cholesterol, fructosamin...

    Authors: G. Misciagna, M. G. Caruso and M. Trevisan
    Citation: Genes & Nutrition 2008 3:80
  40. Tumor microenvironment is essential for tumor cell proliferation, angiogenesis, invasion and metastasis through its provision of survival signals, secretion of growth and pro-angiogenic factors, and direct adh...

    Authors: Domenico Ribatti and Angelo Vacca
    Citation: Genes & Nutrition 2008 3:76

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  • Citation Impact 2023
    Journal Impact Factor: 3.3
    5-year Journal Impact Factor: 3.8
    Source Normalized Impact per Paper (SNIP): 0.644
    SCImago Journal Rank (SJR): 0.838

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    Submission to first editorial decision (median days): 12
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